product summary
Loading...
company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Superoxide Dismutase-1
catalog :
MBS143719
quantity :
1 mg
price :
2650 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS143719
products type :
Recombinant Protein
products full name :
Recombinant Human Superoxide Dismutase-1
products short name :
Superoxide Dismutase-1
products name syn :
SOD1 Human; Superoxide Dismutase 1 Human Recombinant; Superoxide dismutase [Cu-Zn]; EC 1.15.1.1; SOD1; SOD; ALS; ALS1; IPOA
other names :
superoxide dismutase; Superoxide dismutase [Cu-Zn]; superoxide dismutase [Cu-Zn]; superoxide dismutase [Cu-Zn]; Cu/Zn superoxide dismutase; SOD, soluble; epididymis secretory protein Li 44; indophenoloxidase A; superoxide dismutase, cystolic; superoxide dismutase 1, soluble; Superoxide dismutase 1; hSod1
products gene name :
SOD1
other gene names :
SOD1; SOD1; ALS; SOD; ALS1; IPOA; hSod1; HEL-S-44; homodimer; hSod1
uniprot entry name :
SODC_HUMAN
host :
E Coli
sequence length :
154
sequence :
MATKAVCVLK GDGPVQGIIN FEQKESNGPV KVWGSIKGLT EGLHGFHVHE FGDNTAGCTS AGPHFNPLSR KHGGPKDEER HVGDLGNVTA DKDGVADVSI EDSVISLSGD HCIIGRTLVV HEKADDLGKG GNEESTKTGN AGSRLACGVIGIAQ.
purity :
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
SOD1 0.2um filtered solution contains 20mM Tris-HCl pH-7.5 and 10% glycerol. Sterile Filtered colorless solution.
other info2 :
Biological Activity: Specific activity is > 90 units/mg, in which one unit will inhibit the rate of reduction of cytochrome c by 50% in a coupled system, using xanthine and Xanthine oxidase at pH 7.8 at 25C in a 1.5 ml reaction volume.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Superoxide Dismutase
products description :
Description: Recombinant Human Cu/Zn Superoxide Dismutase produced in E Coli is a single monomeric non-glycosylated polypeptide chain containing 154 amino acids and having a total molecular mass of 15.9 kDa.The SOD1 is purified by proprietary chromatographic techniques. Introduction: Human Cu/Zn Superoxide Dismutase (SOD1) catalyzes the reaction between superoxide anions and hydrogen to yield molecular oxygen and hydrogen peroxide. The enzyme protects the cell against dangerous levels of superoxide. SOD1 binds copper and zinc ions and is 1 of 3 isozymes accountable for destroying free superoxide radicals in the body. The encoded protein neutralizes supercharged oxygen molecules, which can damage cells if their levels are not controlled. Mutations in SOD1 cause a form of familial amyotrophic lateral sclerosis.
ncbi gi num :
4507149
ncbi acc num :
NP_000445.1
ncbi gb acc num :
NM_000454.4
uniprot acc num :
P00441
ncbi mol weight :
15,936 Da
ncbi pathways :
AGE/RAGE Pathway 698754!!Amyotrophic Lateral Sclerosis (ALS) Pathway 920975!!Amyotrophic Lateral Sclerosis (ALS) Pathway 83099!!Amyotrophic Lateral Sclerosis (ALS) Pathway 511!!Cellular Responses To Stress Pathway 645258!!Detoxification Of Reactive Oxygen Species Pathway 1127552!!Dopamine Metabolism Pathway 920995!!FOXA1 Transcription Factor Network Pathway 137979!!Folate Metabolism Pathway 198833!!Hemostasis Pathway 106028
ncbi summary :
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]
size :
1 mg
price :
2650 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!