product summary
Loading...
company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Adenine Phosphoribosyltransferase
catalog :
MBS143668
quantity :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS143668
products type :
Recombinant Protein
products full name :
Recombinant Human Adenine Phosphoribosyltransferase
products short name :
Adenine Phosphoribosyltransferase
products name syn :
APRT Human; Adenine Phosphoribosyltransferase Human Recombinant; EC 2.4.2.73; MGC125857; AMP diphosphorylase; Adenine phosphoribosyltransferase; APRT; AMP; MGC125856; MGC129961; DKFZp686D13177
other names :
adenine phosphoribosyltransferase isoform a; Adenine phosphoribosyltransferase; adenine phosphoribosyltransferase; AMP diphosphorylase; AMP pyrophosphorylase; transphosphoribosidase; adenine phosphoribosyltransferase
products gene name :
APRT
other gene names :
APRT; APRT; AMP; APRTD; APRT
uniprot entry name :
APT_HUMAN
host :
E Coli
sequence length :
180
sequence :
MADSELQLVE QRIRSFPDFP TPGVVFRDIS PVLKDPASFR AAIGLLARHL KATHGGRIDY IAGLDSRGFL FGPSLAQELG LGCVLIRKRG KLPGPTLWAS YSLEYGKAEL EIQKDALEPG QRVVVVDDLL ATGGTMNAAC ELLGRLQAEV LECVSLVELT SLKGREKLAP VPFFSLLQYE.
purity :
Greater than 90.0% as determined by SDS-PAGE.
form :
The protein solution contains 20mM Tris-HCl pH-8, 1mM DTT and 10% glycerol. Sterile Filtered colorless solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
products categories :
ENZYMES; Enzymes; Transferase
products description :
Description: APRT Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 180 amino acids (1-180 a.a.) and having a molecular mass of 19.6 kDa. The APRT is purified by conventional chromatography. Introduction: APRT is part of the purine/pyrimidine phosphoribosyltransferase family. APRT enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). APRT produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in APRT causes 2,8-dihydroxyadenine urolithiasis. APRT catalyzes a salvage reaction resulting in the formation of AMP.
ncbi gi num :
4502171
ncbi acc num :
NP_000476.1
ncbi gb acc num :
NM_000485.2
uniprot acc num :
P07741
ncbi mol weight :
14,557 Da
ncbi pathways :
Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Nucleotides Pathway 106263!!Purine Metabolism Pathway 82944!!Purine Metabolism Pathway 106265!!Purine Metabolism Pathway 307!!Purine Salvage Pathway 106273!!Adenine And Adenosine Salvage I Pathway 547494!!Superpathway Of Purine Nucleotide Salvage 907942
ncbi summary :
Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
size :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!