catalog number :
MBS143659
products type :
Native Protein
products full name :
Melanotan-I
products short name :
Melanotan-I
products name syn :
MT I; Melanotan-I; Melanotan-I; MT-I; Melanotan-1
other names :
metallothionein-1; Metallothionein-1; metallothionein-1; MT-1; MT-I; metallothionein-I; metallothionein 1a; Metallothionein-I; MT-I
products gene name :
MT I
other gene names :
Mt1a; Mt1; Mt; Mt1; Mt1a; MT-1; MT-I
uniprot entry name :
MT1_RAT
purity :
Greater than 98.0% as determined by RP-HPLC.
form :
The protein (1 mg/ml) was lyophilized with no additives. Sterile Filtered off-White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Melanotan-I although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution MT-I should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Melanotan-I in sterile 1% acetic acid not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
products categories :
HORMONES; Hormones; Peptide Hormones
products description :
Description: Melanotan-I has the amino acid sequence of Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val and a molecular weight of 1647.4 Dalton.
ncbi acc num :
NP_620181.1
ncbi gb acc num :
NM_138826.4
ncbi mol weight :
6,006 Da
ncbi pathways :
Mineral Absorption Pathway (212234); Mineral Absorption Pathway (212220)
ncbi summary :
may play a role in protecting the ovarian tissues from oxidative stress [RGD, Feb 2006]
uniprot summary :
MT1: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. Belongs to the metallothionein superfamily. Type 1 family. Cellular Component: lysosome; perinuclear region of cytoplasm; cell; cytoplasm; intracellular; cytosol; nucleus. Molecular Function: copper ion binding; zinc ion binding; metal ion binding. Biological Process: cellular metal ion homeostasis; response to zinc ion; cellular zinc ion homeostasis; negative regulation of neuron apoptosis; detoxification of copper ion; nitric oxide mediated signal transduction; negative regulation of growth