Recombinant Human Peroxiredoxin-5 | MyBioSource MBS143654 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Peroxiredoxin-5

catalog :

MBS143654

quantity :

0.02 mg

price :

205 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS143654

products type :

Recombinant Protein

products full name :

Recombinant Human Peroxiredoxin-5

products short name :

Peroxiredoxin-5

products name syn :

PRDX5 Human; Peroxiredoxin-5 Human Recombinant; Peroxiredoxin-5 mitochondrial; Prx-V; Peroxisomal antioxidant enzyme; Thioredoxin reductase; Thioredoxin peroxidase PMP20; Antioxidant enzyme B166; TPx type VI; Liver tissue 2D-page spot 71B; Alu corepressor 1; PLP; ACR1; B166; PRXV; PMP20; PRDX6; SBBI10; AOEB166; MGC117264; MGC142283; MGC142285; PRDX5

other names :

peroxiredoxin-5, mitochondrial isoform a; Peroxiredoxin-5, mitochondrial; peroxiredoxin-5, mitochondrial; Alu co-repressor 1; TPx type VI; antioxidant enzyme B166; epididymis secretory protein Li 55; liver tissue 2D-page spot 71B; peroxiredoxin V; peroxisomal antioxidant enzyme; thioredoxin peroxidase PMP20; thioredoxin reductase; peroxiredoxin 5; Alu corepressor 1; Antioxidant enzyme B166; AOEB166; Liver tissue 2D-page spot 71B; PLP; Peroxiredoxin V; Prx-V; Peroxisomal antioxidant enzyme; TPx type VI; Thioredoxin peroxidase PMP20; Thioredoxin reductase

products gene name :

PRDX5

other gene names :

PRDX5; PRDX5; PLP; ACR1; B166; PRXV; PMP20; PRDX6; prx-V; SBBI10; AOEB166; HEL-S-55; ACR1; AOEB166; Prx-V

uniprot entry name :

PRDX5_HUMAN

host :

E Coli

sequence length :

214

sequence :

MAPIKVGDAI PAVEVFEGEP GNKVNLAELF KGKKGVLFGV PGAFTPGCSK THLPGFVEQA EALKAKGVQV VACLSVNDAF VTGEWGRAHK AEGKVRLLAD PTGAFGKETD LLLDDSLVSI FGNRRLKRFS MVVQDGIVKA LNVEPDGTGL TCSLAPNIIS QL.

purity :

Greater than 95.0% as determined by SDS-PAGE.

form :

The PRDX5 solution contains 20mM HEPES buffer (pH 7.4). Sterile Filtered colorless solution.

storage stability :

PRDX5 although stable 4 degree C for 4 weeks, should be stored desiccated below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

other info2 :

Biological Activity: The specific activity was found to be approximately 117-136 pmole/min/ ug. The enzymatic activity was confirmed by measuring the remaining peroxide after incubation of PRDX5 and peroxide for 20 min at room temperature. Specific activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25 degree C for 1 minute.

products categories :

ENZYMES; Enzymes; Peroxiredoxin

products description :

Description: PRDX5 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 162 amino acids (53-214 a.a.) and having a molecular mass of 17 kDa.The PRDX5 is purified by proprietary chromatographic techniques. Introduction: PRDX5 belongs to the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides with reducing equivalents supplied through the thioredoxin system. PRDX5 has an antioxidant protective function in different tissues under normal conditions and during inflammatory processes. Peroxiredoxin-5 interacts with peroxisome receptor 1 and is involved in intracellular redox signaling. PRDX5 is involved in intracellular redox signaling. Peroxiredoxin-5 is a significant antioxidant protein of lung epithelial cells for its expression in the human lung increases during inflammation. PRDX5 expression is upregulated in osteoarthritis. PRDX5 may be significant in mitochondrial genome stability. Peroxiredoxin-5 has a protective role in human tendon cells against oxidative stress by reducing apoptosis and upholding collagen synthesis.

ncbi gi num :

6912238

ncbi acc num :

NP_036226.1

ncbi gb acc num :

NM_012094.4

uniprot acc num :

P30044

ncbi mol weight :

12,897 Da

ncbi pathways :

Cellular Responses To Stress Pathway 645258!!Detoxification Of Reactive Oxygen Species Pathway 1127552!!Peroxisome Pathway 131226!!Peroxisome Pathway 131126!!Selenium Pathway 198825!!Thioredoxin Pathway 142228

ncbi summary :

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms. Three transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

size :

0.02 mg

price :

205 USD

more info or order :

MyBioSource product webpage