product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Frataxin
catalog :
MBS143636
quantity :
1 mg
price :
3465 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS143636
products type :
Recombinant Protein
products full name :
Recombinant Human Frataxin
products short name :
Frataxin
products name syn :
Frataxin Human; Frataxin Human Recombinant; FXN; Friedreich ataxia protein; Frataxin mitochondrial; FRDA; X25; FA; CyaY; FARR; MGC57199; Frataxin; Frataxin
other names :
frataxin, mitochondrial isoform 1 preproprotein; Frataxin, mitochondrial; frataxin, mitochondrial; Friedreich ataxia protein; frataxin; Friedreich ataxia protein; Fxn
other gene names :
FXN; FXN; FA; X25; CyaY; FARR; FRDA; FRDA; X25; Fxn; i-FXN
uniprot entry name :
FRDA_HUMAN
host :
E Coli
sequence length :
210
purity :
Greater than 95.0% as determined by SDS-PAGE.
form :
The Frataxin solution contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT and 10% glycerol. Sterile Filtered colorless solution.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins
products description :
Description: Frataxin Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 190 amino acids (42-210 a.a.) and having a molecular mass of 21.1 kDa. The Frataxin is fused to a 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques. Introduction: Frataxin is a mitochondrial iron binding protein that is part of the FRATAXIN family. Frataxin functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Frataxin plays a role in iron homeostasis. Frataxin is an anti-apoptotic protein which prevents mitochondrial damage and reactive oxygen species (ROS) production.
ncbi gi num :
31077081
ncbi acc num :
NP_000135.2
ncbi gb acc num :
NM_000144.4
uniprot acc num :
Q16595
ncbi mol weight :
21,416 Da
ncbi pathways :
HIF-2-alpha Transcription Factor Network Pathway 137956!!Metabolism Pathway 477135!!Metabolism Of Proteins Pathway 106230!!Mitochondrial Iron-sulfur Cluster Biogenesis Pathway 730343!!Mitochondrial Protein Import Pathway 576261
ncbi summary :
This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]
size :
1 mg
price :
3465 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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