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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Serpin Peptidase Inhibitor, Clade B Member 5, His Tag
catalog :
MBS143635
quantity :
1 mg
price :
2665 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS143635
products type :
Recombinant Protein
products full name :
Recombinant Human Serpin Peptidase Inhibitor, Clade B Member 5, His Tag
products short name :
Serpin Peptidase Inhibitor
products name syn :
SERPINB5 Human, His; Serpin Peptidase Inhibitor, Clade B Member 5 Human Recombinant, His tag; PI5; maspin; SERPINB5; serpin peptidase inhibitor clade B (ovalbumin) member 5; Serpin B5; Protease inhibitor 5; SERPINB5 His
other names :
serpin B5; Serpin B5; serpin B5; PI-5; peptidase inhibitor 5; protease inhibitor 5 (maspin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5; serpin peptidase inhibitor, clade B (ovalbumin), member 5; Maspin; Peptidase inhibitor 5; PI-5
products gene name :
SERPINB5
other gene names :
SERPINB5; SERPINB5; PI5; maspin; PI5; PI-5
uniprot entry name :
SPB5_HUMAN
host :
E Coli
sequence length :
375
sequence :
MGSSHHHHHH SSGLVPRGSH MDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHF ENVKDVPFGF QTVTSDVNKL SSFYSLKLIK RLYVDKSLNL STEFISSTKR PYAKELETVD FKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKILVVNAAYFVGK WMKKFPESET KECPFRVNKT DTKPVQMMNM EATFCMGNID SINCKIMELP FQNKHLSMFI LLPKDVEDES TGLEKIEKQLNSESLSQWTN PSTMANAKVK LSIPKFKVEK MIDPKACLEN LGLKHIFSED TSDFSGMSET KGVALSNVIH KVCLEITEDG GDSIEVPGAR ILQHKDELNA DHPFIYIIRH NKTRNIIFFG KFCSP.
purity :
Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
The SERPINB5 solution contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 10% glycerol. Sterile Filtered colorless solution.
storage stability :
SERPINB5 although stable 4 degree C for 4 weeks, should be stored desiccated below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Serpin
products description :
Description: SERPINB5 Human Recombinant fused with 20 amino acid His tag at N-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain containing 395 amino acids (1-375 a.a.) and having a molecular mass of 44.2 kDa.The SERPINB5 is purified by proprietary chromatographic techniques. Introduction: SERPINB5 (Maspin) is a tumor suppressor protein of the serine proteinase inhibitor family. Maspin plays a vital role in embryonic development through critical functions in cell adhesion. In addition, Maspin is present in normal breast and prostatic epithelial cells although down regulated in the particular carcinomas. SERPINB5 impedes the growth, invasion, and metastatic properties of mammary tumors as well as the invasive ability of pancreatic ductal adenocarcinoma cells. SERPINB5 being a breast tumor suppressor gene is a significant marker of the disease progression in breast neoplasms. Furthermore, high expression of maspin is linked to squamous cell carcinoma in non-small-cell lung cancer. Moreover, maspin expression has been directly linked with the biological aggressiveness of ovarian carcinoma. Maspin exhibits no serine protease inhibitory activity since it does not undergo the stressed to relaxed conformational transition typical of active serpins.
ncbi gi num :
167860126
ncbi acc num :
NP_002630.2
ncbi gb acc num :
NM_002639.4
uniprot acc num :
P36952
ncbi mol weight :
25,763 Da
ncbi pathways :
ATF-2 Transcription Factor Network Pathway 138006!!Direct P53 Effectors Pathway 137939!!MicroRNAs In Cancer Pathway 852705!!MicroRNAs In Cancer Pathway 852928!!P53 Signaling Pathway 83055!!P53 Signaling Pathway 465
size :
1 mg
price :
2665 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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