product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Annexin A3
catalog :
MBS143632
quantity :
0.005 mg
price :
140 USD
more info or order :
product information
catalog number :
MBS143632
products type :
Recombinant Protein
products full name :
Recombinant Human Annexin A3
products short name :
Annexin A3
products name syn :
ANXA3 Human; Annexin A3 Human Recombinant; ANX3; ANXA3; Annexin-III; Lipocortin-3; Lipocortin-III; Annexin-3; Annexin A3; Placental anticoagulant protein III; PAP-III; 35-alpha calcimedin; Inositol 1; 2-cyclic phosphate 2-phosphohydrolase
other names :
annexin A3; Annexin A3; annexin A3; 35-alpha calcimedin; Annexin III (lipocortin III); PAP-III; annexin III (lipocortin III, 1,2-cyclic-inositol-phosphate phosphodiesterase, placental anticoagulant protein III, calcimedin 35-alpha); annexin-3; inositol 1,2-cyclic phosphate 2-phosphohydrolase; annexin A3; 35-alpha calcimedin; Annexin III; Annexin-3; Inositol 1,2-cyclic phosphate 2-phosphohydrolase; Lipocortin III; Placental anticoagulant protein III; PAP-III
products gene name :
ANXA3
other gene names :
ANXA3; ANXA3; ANX3; ANX3; PAP-III
uniprot entry name :
ANXA3_HUMAN
host :
E Coli
sequence length :
323
sequence :
MASIWVGHRG TVRDYPDFSP SVDAEAIQKA IRGIGTDEKM LISILTERSN AQRQLIVKEY QAAYGKELKD DLKGDLSGHF EHLMVALVTP PAVFDAKQLK KSMKGAGTNE DALIEILTTR TSRQMKDISQ AYYTVYKKSL GDDISSETSG DFRKALLTLA DGRRDESLKV DEHLAKQDAQ ILYKAGENRW GTDEDKFTEI LCLRSFPQLK LTFDEYRNIS QKDIVDSIKG ELSGHFEDLL LAIVNCVRNT PAFLAERLHR ALKGIGTDEF TLNRIMVSRS EIDLLDIRTE FKKHYGYSLY SAIKSDTSGD YEITLLKICG GDD.
purity :
Greater than 90% as determined by SDS-PAGE.
form :
The ANXA3 protein solution contains 20mM Tris-HCl, pH-7.5, 1mM DTT and 10% glycerol. Sterile filtered colorless solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Annexin
products description :
Description: ANXA3 produced in E Coli is a single, non-glycosylated polypeptide chain containing 323 amino acids (1-323 a.a.) and having a molecular mass of 36.3 kDa. ANXA3 is purified by proprietary chromatographic techniques. Introduction: ANXA3 is an inhibitor of phospholipase A2. ANXA3 possesses anti-coagulant properties. ANXA3 cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. ANXA3 is part of the annexin family which are members of the calcium-dependent phospholipid-binding protein family that are involved in the regulation of cellular growth and in signal transduction pathways. ANXA3 takes part as an anti-coagulation factor.
ncbi gi num :
4826643
ncbi acc num :
NP_005130.1
ncbi gb acc num :
NM_005139.2
uniprot acc num :
P12429
ncbi mol weight :
36,375 Da
ncbi pathways :
Prostaglandin Synthesis And Regulation Pathway (198912)
ncbi summary :
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation. [provided by RefSeq, Jul 2008]
uniprot summary :
ANXA3: a calcium/phospholipid-binding protein and inhibitor of phospholipase A2, Possesses anti-coagulant properties. Cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion. Protein type: Calcium-binding. Chromosomal Location of Human Ortholog: 4q21.21. Cellular Component: specific granule; phagocytic vesicle membrane; membrane; cytoplasm; plasma membrane. Molecular Function: calcium-dependent phospholipid binding; phospholipase A2 inhibitor activity; calcium ion binding; calcium-dependent protein binding. Biological Process: positive regulation of angiogenesis; negative regulation of catalytic activity; neutrophil degranulation; defense response to bacterium; positive regulation of transcription factor activity; phagocytosis
size1 :
0.005 mg
price1 :
140 USD
size2 :
0.02 mg
price2 :
205
size3 :
1 mg
price3 :
2220
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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