protein

Recombinant Human APO-D GST Tag

MBS143615

0.01 mg

610 USD

Recombinant Protein

Recombinant Human APO-D GST Tag

APO-D

APO D Human, GST; APO-D Human Recombinant, GST Tag; Apolipoprotein D; Apo-D; ApoD; APOD GST

apolipoprotein D; Apolipoprotein D; apolipoprotein D; apo-D; apolipoprotein D

APOD

APOD; APOD; Apo-D; ApoD

APOD_HUMAN

E Coli

189

APO-D protein at 100 ug/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol. Sterile Filtered clear solution.

Store vial at -20 degree C to -80 degree C. When stored at the recommended temperature, this protein is stable for 12 months.

CYTOKINES AND GROWTH FACTORS; Cytokines; Apolipoprotein

Description: APO-D Human Recombinant full length protein expressed in E Coli, shows a 48 kDa band on SDS-PAGE.The APO-D is purified by proprietary chromatographic techniques. Introduction: Apolipoprotein-D is mainly associated with high density lipoproteins in human plasma. Apolipoprotein-D is an atypical apolipoprotein and, based on its primary structure, Apolipoprotein-D is a member of the lipocalin family. Lipocalins adopt a beta-barrel tertiary structure and transport small hydrophobic ligands. Apolipoprotein-D binds cholesterol, progesterone, pregnenolone, bilirubin and arachidonic acid. Apolipoprotein-D is expressed in numerous tissues having high levels of expression in spleen, testes and brain. Apolipoprotein-D is present at high concentrations in the cyst fluid of women with gross cystic disease of the breast, a condition associated with increased risk of breast cancer. Apolipoprotein-D accumulates in regenerating peripheral nerves and in the cerebrospinal fluid of patients with neurodegenerative conditions, such as Alzheimer's disease. Apolipoprotein-D participates in maintenance and repair within the central and peripheral nervous systems. Apolipoprotein-D is a multi-ligand, multi-functional transporter and transports a ligand from 1 cell to another within an organ, scavenge a ligand within an organ for transport to the blood or could transport a ligand from the circulation to specific cells within a tissue.

4502163

NP_001638.1

NM_001647.3

P05090

21,276 Da

Orphan Transporters Pathway 1127546!!SLC-mediated Transmembrane Transport Pathway 119558!!Transmembrane Transport Of Small Molecules Pathway 106572!!Transport Of Fatty Acids Pathway 187185!!Transport Of Vitamins, Nucleosides, And Related Molecules Pathway 161075

This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism. [provided by RefSeq, Aug 2008]

0.01 mg

610 USD