catalog number :
MBS143604
products type :
Recombinant Protein
products full name :
Recombinant Human Pentraxin-3
products short name :
Pentraxin-3
products name syn :
PTX3 Human; Pentraxin-3 Human Recombinant; TSG-14; TNFAIP5; PTX3; Pentraxin-related protein PTX3; Pentaxin-related protein PTX3; Tumor necrosis factor-inducible gene 14 protein; TSG14; pentraxin-related gene rapidly induced by IL-1 beta
other names :
pentraxin-related protein PTX3; Pentraxin-related protein PTX3; pentraxin-related protein PTX3; TNF alpha-induced protein 5; pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, alpha-induced protein 5; pentaxin-related protein PTX3; pentraxin-3; pentraxin-related gene, rapidly induced by IL-1 beta; tumor necrosis factor alpha-induced protein 5; tumor necrosis factor-inducible gene 14 protein; tumor necrosis factor-inducible protein TSG-14; pentraxin 3, long; Pentaxin-related protein PTX3; Tumor necrosis factor alpha-induced protein 5; TNF alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; TSG-14
products gene name :
PTX3
other gene names :
PTX3; PTX3; TSG-14; TNFAIP5; TNFAIP5; TSG14; TNF alpha-induced protein 5; TSG-14
uniprot entry name :
PTX3_HUMAN
purity :
Greater than 90% as determined by Analysis by SDS-PAGE.
form :
The PTX3 protein contains 20mM Tris-HCl buffer pH-8.5, 1mM DTT and 10% glycerol. Sterile filtered colorless solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins
products description :
Description: Recombinant Human PTX3 produced in E Coli is a single, non-glycosylated polypeptide chain containing 401 amino acids (18-381 a.a) and having a molecular mass of 44.4 kDa. PTX3 is fused to a 36 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques. Introduction: PTX3 is part of the pentraxin family sharing the C-terminal domain with short pentraxins and containing a unique N-terminal domain. PTX3 is produced and released at inflammatory sites by various cell types including monocytes/macrophages, endothelial cells, vascular smooth muscle cells, fibroblasts, and adipocytes. PTX3 is involved in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. PTX3 is used as a marker for disease activity of psoriasis. High serum PTX3 levels are associated with the disease severity of systemic sclerosis. Elevated serum PTX3 is associated with pulmonary fungal infections.
ncbi acc num :
NP_002843.2
ncbi gb acc num :
NM_002852.3
ncbi mol weight :
41,976 Da