catalog number :
MBS143570
products type :
Recombinant Protein
products full name :
Recombinant Human Glutathione S-Transferase Kappa 1
products short name :
Glutathione S-Transferase Kappa 1
products name syn :
GSTK1 Human; Glutathione S-Transferase Kappa 1 Human Recombinant; GST13; GST13-13; GSTK1-1; GST class-kappa; EC 2.5.1.18; Glutathione S-transferase kappa 1; Glutathione S-transferase subunit 13; hGSTK1; GSTK1
other names :
glutathione S-transferase kappa 1 isoform b; Glutathione S-transferase kappa 1; glutathione S-transferase kappa 1; GST class-kappa; glutathione S-transferase k1; glutathione S-transferase subunit 13 homolog; glutathione S-transferase kappa 1; GST 13-13; GST class-kappa; GSTK1-1; hGSTK1; Glutathione S-transferase subunit 13
products gene name :
GSTK1
other gene names :
GSTK1; GSTK1; GST; GST13; hGSTK1; GSTK1-1; GST13-13; GST 13-13; hGSTK1
uniprot entry name :
GSTK1_HUMAN
sequence :
MGPLPRTVEL FYDVLSPYSW LGFEILCRYQ NIWNINLQLR PSLITGIMKD SGNKPPGLLP RKGLYMANDL KLLRHHLQIP IHFPKDFLSV MLEKGSLSAM RFLTAVNLEH PEMLEKASRE LWMRVWSRNE DITEPQSILA AAEKAGMSAE QAQGLLEKIA TPKVKNQLKE TTEAACRYGA FGLPITVAHV DGQTHMLFGS DRMELLAHLL GEKWMGPIPP AVNARL.
purity :
Greater than 90% as determined by SDS-PAGE.
form :
GSTK1 solution containing 20mM Tris pH-8, 1mM DTT and 10% glycerol. Sterile filtered colorless solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
products categories :
ENZYMES; Enzymes; Transferase
products description :
Description: GSTK1 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 226 amino acids (1-226 a.a.) and having a molecular mass of 25.5 kDa. GSTK1 is purified by proprietary chromatographic techniques. Introduction: GSTK1 is involved in cellular detoxification. GSTK1 is localized to the peroxisome and catalyzes the conjugation of the thiol group of glutathione (GSH) to the electrophilic groups of a broad range of hydrophobic substrates, leading to an easier removal of the latter from the cells.
ncbi acc num :
NP_001137151.1
ncbi gb acc num :
NM_001143679.1
ncbi mol weight :
20,538 Da
ncbi pathways :
Chemical Carcinogenesis Pathway 673221!!Chemical Carcinogenesis Pathway 673237!!Drug Metabolism - Cytochrome P450 Pathway 83032!!Drug Metabolism - Cytochrome P450 Pathway 427!!Glutathione Metabolism Pathway 82973!!Glutathione Metabolism Pathway 343!!Metabolism Of Xenobiotics By Cytochrome P450 Pathway 83031!!Metabolism Of Xenobiotics By Cytochrome P450 Pathway 425!!Peroxisome Pathway 131226!!Peroxisome Pathway 131126
ncbi summary :
This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]