product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Aldo-Keto Reductase Family 7 Member A3
catalog :
MBS143526
quantity :
0.01 mg
price :
205 USD
more info or order :
product information
catalog number :
MBS143526
products type :
Recombinant Protein
products full name :
Recombinant Human Aldo-Keto Reductase Family 7 Member A3
products short name :
Aldo-Keto Reductase Family 7 Member A3
products name syn :
AKR7A3 Human; Aldo-Keto Reductase Family 7 Member A3 Human Recombinant; AFAR2; Aflatoxin B1 aldehyde reductase member 3; AFB1 aldehyde reductase 2; AFB1-AR 2; AKR7A3
other names :
aflatoxin B1 aldehyde reductase member 3; Aflatoxin B1 aldehyde reductase member 3; aflatoxin B1 aldehyde reductase member 3; AFB1 aldehyde reductase 2; AFB1-AR 2; aflatoxin B1 aldehyde reductase 2; aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase); AFB1 aldehyde reductase 2; AFB1-AR 2
products gene name :
AKR7A3
other gene names :
AKR7A3; AKR7A3; AFAR2; AFAR2; AFB1-AR 2
uniprot entry name :
ARK73_HUMAN
host :
E Coli
sequence length :
331
sequence :
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSELEM SRQLSRARPA TVLGAMEMGR RMDAPTSAAV TRAFLERGHT EIDTAFVYSE GQSETILGGL GLRLGGSDCR VKIDTKAIPL FGNSLKPDSL RFQLETSLKR LQCPRVDLFY LHMPDHSTPV EETLRACHQL HQEGKFVELG LSNYAAWEVA EICTLCKSNG WILPTVYQGM YNAITRQVET ELFPCLRHFG LRFYAFNPLA GGLLTGKYKY EDKDGKQPVG RFFGNTWAEM YRNRYWKEHH FEGIALVEKA LQAAYGASAP SMTSATLRWM YHHSQLQGAH GDAVILGMSS LEQLEQNLAA AEEGPLEPAV VDAFNQAWHL VAHECPNYFR.
purity :
Greater than 95.0% as determined by SDS-PAGE.
form :
The AKR7A3 solution contains 20mM Tris-HCl pH-8, 0.1M NaCl and 10% glycerol. Sterile Filtered clear colorless solution.
other info2 :
Biological Activity: Specific activity: approximately < 0.1 units/mg.Enzymatic activity was confirmed by measuring the amount of enzyme catalyzing the oxidation of 1 micromole NADPH per minute at 25C. Specific activity was expressed as units/mg protein.
products categories :
ENZYMES; Enzymes; Reductase
products description :
Description: AKR7A3 Human Recombinant fused to 39 amino acid His Tag at N-terminal produced in E Coli is a single, non-glycosylated, polypeptide chain containing 370 amino acids (1-331 a.a.) and having a molecular mass of 41.6 kDa. The AKR7A3 is purified by proprietary chromatographic techniques. Introduction: AKR7A3, takes part in the detoxification of aldehydes and ketones. AKR7A3 reduces the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. AKR7A3 participates in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
ncbi gi num :
41152114
ncbi acc num :
NP_036199.2
ncbi gb acc num :
NM_012067.2
uniprot acc num :
O95154
ncbi mol weight :
37,206 Da
ncbi pathways :
Aflatoxin B1 Metabolism Pathway 198808!!Aflatoxin Activation And Detoxification Pathway 1127511!!Biological Oxidations Pathway 105698!!Defective ACY1 Causes Encephalopathy Pathway 1127638!!Disease Pathway 530764!!Metabolic Disorders Of Biological Oxidation Enzymes Pathway 1127637!!Metabolism Pathway 477135!!Metabolism Of Xenobiotics By Cytochrome P450 Pathway 83031!!Metabolism Of Xenobiotics By Cytochrome P450 Pathway 425!!Metapathway Biotransformation 198837
ncbi summary :
Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.[supplied by OMIM, Apr 2004]
size :
0.01 mg
price :
205 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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