product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human WNT Inhibitory Factor 1
catalog :
MBS143513
quantity :
0.01 mg
price :
410 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS143513
products type :
Recombinant Protein
products full name :
Recombinant Human WNT Inhibitory Factor 1
products short name :
WNT Inhibitory Factor 1
products name syn :
WIF1 Human; WNT Inhibitory Factor 1 Human Recombinant; WIF1; WIF-1; Wnt inhibitory factor 1
other names :
wnt inhibitory factor 1; Wnt inhibitory factor 1; wnt inhibitory factor 1; WNT inhibitory factor 1
products gene name :
WIF1
other gene names :
WIF1; WIF1; WIF-1; WIF-1
uniprot entry name :
WIF1_HUMAN
host :
Hi-5 Cells
sequence length :
379
purity :
Greater than 80.0% as determined by SDS-PAGE.
form :
The WIF1 protein solution contains 1X PBS pH 7.4, 10% glycerol and 1mM PMSF. Sterile filtered colorless solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins
products description :
Description: WIF1 produced in Hi-5 cells is a single, glycosylated polypeptide chain containing 369 amino acids (29-379 a.a.) and having a molecular mass of 40.5 kDa, (48kDa on SDS-PAGE). WIF1 is fused to 16 amino acid His Tag at C-Terminus and purified by proprietary chromatographic techniques. Introduction: WIF1 binds to wnt proteins and inhibits their activities. WIF1 plays a role in mesoderm segmentation. WNT proteins are extracellular signaling molecules that take part in the control of embryonic development & cancer. WIF1 protein contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. WIF1 takes part in mesoderm segmentation. WIF1 protein is found to be present in fish, amphibia and mammals. WIF1 is a recurrent target in human salivary gland oncogenesis. Downregulation of WIF1 takes part in the development and progression of pleomorphic adenomas. WIF1 is a tumor suppressor, specifically in nonfunctioning pituitary tumors.
ncbi gi num :
111125011
ncbi acc num :
NP_009122.2
ncbi gb acc num :
NM_007191.4
uniprot acc num :
Q9Y5W5
ncbi mol weight :
41,528 Da
ncbi pathways :
Disease Pathway 530764!!Presenilin Action In Notch And Wnt Signaling Pathway 137914!!RNF Mutants Show Enhanced WNT Signaling And Proliferation Pathway 1127632!!Signal Transduction Pathway 477114!!Signaling By WNT In Cancer Pathway 1127614!!Signaling By Wnt Pathway 106510!!TCF Dependent Signaling In Response To WNT Pathway 1127516!!Wnt Signaling Network Pathway 137962!!Wnt Signaling Pathway 83061!!Wnt Signaling Pathway 471
ncbi summary :
The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. [provided by RefSeq, Jun 2010]
size :
0.01 mg
price :
410 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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