protein

Recombinant Human Transcription Elongation Factor B Polypeptide 2

MBS143507

0.01 mg

140 USD

Recombinant Protein

Recombinant Human Transcription Elongation Factor B Polypeptide 2

Transcription Elongation Factor B Polypeptide 2

TCEB2 Human; Transcription Elongation Factor B Polypeptide 2 Human Recombinant; ELOB; SIII; Elongin B; Transcription elongation factor B polypeptide 2; RNA polymerase II transcription factor SIII subunit B; SIII p18; Elongin 18 kDa subunit; TCEB2

transcription elongation factor B polypeptide 2 isoform a; Transcription elongation factor B polypeptide 2; transcription elongation factor B polypeptide 2; RNA polymerase II transcription factor SIII p18 subunit; RNA polymerase II transcription factor SIII subunit B; elongin 18 kDa subunit; elongin, 18-kD subunit; elongin-B; transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B); Elongin 18 kDa subunit; Elongin-B; EloB; RNA polymerase II transcription factor SIII subunit B; SIII p18

TCEB2

TCEB2; TCEB2; ELOB; SIII; EloB

ELOB_HUMAN

E Coli

118

MDVFLMIRRH KTTIFTDAKE SSTVFELKRI VEGILKRPPD EQRLYKDDQL LDDGKTLGEC GFTSQTARPQ APATVGLAFR ADDTFEALCIEPFSSPPELP DVMKPQDSGS SANEQAVQ.

Greater than 95.0% as determined by SDS-PAGE.

The TCEB2 protein solution contains 20mM Tris-HCl pH-8, 1mM DTT, 0.1mM PMSF, and 20% glycerol. Sterile Filtered colorless solution.

TCEB2 although stable 4 degree C for 4 weeks, should be stored desiccated below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Transcription Elongation Factor

Description: TCEB2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 118 amino acids (1-118) and having a molecular mass of 13.1 kDa. TCEB2 is purified by standard chromatography techniques. Introduction: TCEB2 is a subunit of the SIIII complex which is a heterotrimer consisting of a transcriptionally active subunit (A) and two regulatory subunits (B and C). TCEB2 initiates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.

6005890

NP_009039.1

NM_007108.3

Q15370

17,911 Da

Adaptive Immune System Pathway 366160!!Antigen Processing: Ubiquitination Proteasome Degradation Pathway 366162!!Cellular Response To Hypoxia Pathway 645259!!Cellular Responses To Stress Pathway 645258!!Class I MHC Mediated Antigen Processing Presentation Pathway 366161!!Disease Pathway 530764!!ECS Complex Pathway 413455!!ECS Complex Pathway 468394!!ECV Complex Pathway 413450!!ECV Complex Pathway 890606

This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, Aug 2008]

0.01 mg

140 USD