catalog number :
MBS143503
products type :
Recombinant Protein
products full name :
Recombinant Human Esterase D,S-Formylglutathione Hydrolase
products short name :
Esterase D,S-Formylglutathione Hydrolase
products name syn :
Esterase D Human; Esterase D,S-Formylglutathione Hydrolase Human Recombinant; S-formylglutathione hydrolase; FGH; Esterase D; ESD; FLJ11763; esterase D/formylglutathione hydrolase; Esterase-D
other names :
S-formylglutathione hydrolase; S-formylglutathione hydrolase; S-formylglutathione hydrolase; esterase 10; esterase D/formylglutathione hydrolase; methylumbelliferyl-acetate deacetylase; esterase D; Esterase D; Methylumbelliferyl-acetate deacetylase (EC:3.1.1.56)
other gene names :
ESD; ESD; FGH; FGH
uniprot entry name :
ESTD_HUMAN
sequence :
MGSSHHHHHH SSGLVPRGSH MALKQISSNK CFGGLQKVFE HDSVELNCKM KFAVYLPPKA ETGKCPALYW LSGLTCTEQN FISKSGYHQS ASEHGLVVIA PDTSPRGCNI KGEDESWDFG TGAGFYVDAT EDPWKTNYRM YSYVTEELPQ LINANFPVDP QRMSIFGHSM GGHGALICAL KNPGKYKSVS AFAPICNPVL CPWGKKAFSG YLGTDQSKWK AYDATHLVKS YPGSQLDILI DQGKDDQFLL DGQLLPDNFI AACTEKKIPV VFRLQEDYDH SYYFIATFIT DHIRHHAKYL NA.
purity :
Greater than 95.0% as determined by SDS-PAGE.
form :
The Esterase-D solution contains 20mM Tris-HCl buffer (pH8.0) and 10% glycerol. Sterile Filtered colorless solution.
storage stability :
Esterase-D although stable 4 degree C for 4 weeks, should be stored desiccated below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
products categories :
ENZYMES; Enzymes; Esterase
products description :
Description: Esterase-D Human Recombinant fused with 20 amino acid His tag at N-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain containing 302 amino acids (1-282 a.a.) and having a molecular mass of 33.6kDa.The Esterase-D is purified by proprietary chromatographic techniques. Introduction: Formylglutathione hydrolase (Esterase D) is a member of the esterase D family. Esterase D is a serine hydrolase involved in the detoxification of formaldehyde. Esterase D is active toward various substrates including O-acetylated sialic acids, and it may possibly be involved in the recycling of sialic acids. Esterase D is used as a genetic marker for retinoblastoma and Wilson's disease.
ncbi acc num :
NP_001975.1
ncbi gb acc num :
NM_001984.1
ncbi mol weight :
31,463 Da
ncbi pathways :
Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Phase I, Non P450 Pathway 198854!!Formaldehyde Oxidation Pathway 545343
ncbi summary :
This gene encodes a serine hydrolase that belongs to the esterase D family. The encoded enzyme is active toward numerous substrates including O-acetylated sialic acids, and it may be involved in the recycling of sialic acids. This gene is used as a genetic marker for retinoblastoma and Wilson's disease. [provided by RefSeq, Feb 2009]