protein

Recombinant Bovine Growth Hormone

MBS143497

0.02 mg

140 USD

Recombinant Protein

Recombinant Bovine Growth Hormone

BGrowth Hormone

GH Bovine; Growth Hormone Bovine Recombinant; BGH; BST; rBGH; rBST; Bovine Somatotropin; Bovine GH; Growth hormone; GH1

somatotropin; Somatotropin; somatotropin; Growth hormone

bGH

GH1; GH1; GH; GH

SOMA_BOVIN

E Coli

217

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Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.

The Bovine Growth Hormone protein was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3 adjusted to pH-8. Sterile Filtered White lyophilized (freeze-dried) powder.

1mg/ml

Lyophilized Bovine Growth Hormone although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution GH Bovine should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Solubility: It is recommended to reconstitute the lyophilized Bovine Growth Hormone in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Protein Content: Protein quantitation was carried out by two independent methods:1. UV spectroscopy at 280 nm using the absorbency value of 0.68 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a calibrated solution of GH as a Reference Standard. Biological Activity: The activity as determined by the PDFP13B9 cells stably transfected with rabbit GH receptors. Bovine GH is also capable of forming a 1:2 complex with the recombinant ovine growth hormone receptor extracellular domain (ECD).

CYTOKINES AND GROWTH FACTORS; Growth Factors; Growth Hormone

Description: Growth Hormone Bovine Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 191 amino acids and having a molecular mass of 21.8 kDa. The GH Bovine Recombinant is purified by proprietary chromatographic techniques. Introduction: GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.

30794288

NP_851339.1

NM_180996.1

P01246

24,558 Da

Cytokine Signaling In Immune System Pathway (1119410); Growth Hormone Receptor Signaling Pathway (1119427); Immune System Pathway (1119286); Jak-STAT Signaling Pathway (84316); Jak-STAT Signaling Pathway (488); Metabolism Of Proteins Pathway (1119622); Neuroactive Ligand-receptor Interaction Pathway (84292); Neuroactive Ligand-receptor Interaction Pathway (462); Nuclear Signaling By ERBB4 Pathway (1120138); PI3K-Akt Signaling Pathway (692236)

0.02 mg

140 USD

0.1 mg

205

1 mg

725