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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Ornithine Aminotransferase
catalog :
MBS143496
quantity :
1 mg
price :
2220 USD
more info or order :
product information
catalog number :
MBS143496
products type :
Recombinant Protein
products full name :
Recombinant Human Ornithine Aminotransferase
products short name :
Ornithine Aminotransferase
products name syn :
Ornithine Aminotransferase Human; Ornithine Aminotransferase Human Recombinant; DKFZp781A11155; HOGA; OATASE; Ornithine aminotransferase mitochondrial; Ornithine--oxo-acid aminotransferase; OAT; OKT; GACR; Ornithine
other names :
ornithine aminotransferase, mitochondrial isoform 1; Ornithine aminotransferase, mitochondrial; ornithine aminotransferase, mitochondrial; gyrate atrophy; ornithine delta-aminotransferase; ornithine-oxo-acid aminotransferase; ornithine aminotransferase; Ornithine delta-aminotransferase; Ornithine--oxo-acid aminotransferaseCleaved into the following 2 chains:Ornithine aminotransferase, hepatic form; Ornithine aminotransferase, renal form
other gene names :
OAT; OAT; OKT; GACR; HOGA; OATASE
uniprot entry name :
OAT_HUMAN
host :
E Coli
sequence length :
439
sequence :
MTVQGPPTSD DIFEREYKYG AHNYHPLPVA LERGKGIYLW DVEGRKYFDF LSSYSAVNQG HCHPKIVNAL KSQVDKLTLT SRAFYNNVLG EYEEYITKLF NYHKVLPMNT GVEAGETACK LARKWGYTVK GIQKYKAKIV AAGNFWGRT LSAISSSTDP TSYDGFGPFM PGFDIIPYND LPALERALQD PNVAAFMVEP IQGEAGVVVP DPGYLMGVRE LCTRHQVLFI ADEIQTGLAR TGRWLAVDYE NVRPDIVLLG KALSGGLYPV SAVLCDDDIM LTIKPGEHGS TYGGNPLGCR VAIAALEVLE EENLAENADK LGIILRNELM KLPSDVVTAV RGKGLLNAIV IKETKDWDAW KVCLRLRDNG LLAKPTHGDI IRFAPPLVIK EDELRESIEI INKTILSF.
purity :
Greater than 90.0% as determined by SDS-PAGE.
form :
The Ornithine Aminotransferase protein solution contains 20mM Tris, pH-8, and 10% glycerol. Sterile filtered colorless solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
products categories :
ENZYMES; Enzymes; Transferase
products description :
Description: Ornithine Aminotransferase Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 408 amino acids (33-439 a.a.) and having a molecular wieght of 45.2kDa.The Ornithine Aminotransferase is purified by proprietary chromatographic techniques. Introduction: Ornithine Aminotransferase is a mitochondrial enzyme which is an important factor that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Ornithine Aminotransferase mutations result in a deficiency that cause the autosomal recessive eye disease Gyrate Atrophy.
ncbi gi num :
4557809
ncbi acc num :
NP_000265.1
ncbi gb acc num :
NM_000274.3
uniprot acc num :
P04181
ncbi mol weight :
32,853 Da
ncbi pathways :
Amino Acid Synthesis And Interconversion (transamination) Pathway 106173!!Arginine And Proline Metabolism Pathway 82957!!Arginine And Proline Metabolism Pathway 323!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Amino Acids And Derivatives Pathway 106169!!Urea Cycle And Metabolism Of Amino Groups Pathway 198758!!Arginine Degradation I (arginase Pathway) 138167!!Citrulline Biosynthesis Pathway 138212!!Ornithine De Novo Biosynthesis Pathway 142133
ncbi summary :
This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome. [provided by RefSeq, Jan 2010]
size :
1 mg
price :
2220 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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