protein

Human Dipeptidyl-Peptidase 4

MBS143481

10 ng

205 USD

Native Protein

Human Dipeptidyl-Peptidase 4

Dipeptidyl-Peptidase 4

DPP4 Human; Human Dipeptidyl Peptidase-IV; DPP-IV; DPPIV; DPP4; DPP-4; Dipeptidyl Peptidase-IV; Dipeptidyl Peptidase-4; CD26; adenosine deaminase complexing protein 2; Dipeptidylpeptidase-IV; CD-26; ADABP; ADCP2; DPIV; TP103; DP-IV; DP-4; DP4

dipeptidyl peptidase 4; Dipeptidyl peptidase 4; dipeptidyl peptidase 4; ADCP-2; DPP IV; T-cell activation antigen CD26; adenosine deaminase complexing protein 2; dipeptidyl peptidase IV; dipeptidylpeptidase 4; dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); dipeptidyl-peptidase 4; ADABP; Adenosine deaminase complexing protein 2; ADCP-2; Dipeptidyl peptidase IV; DPP IV; T-cell activation antigen CD26; TP103; CD_antigen: CD26Cleaved into the following 2 chains:Dipeptidyl peptidase 4 membrane formAlternative name(s):Dipeptidyl peptidase IV membrane form

DPP4

DPP4; DPP4; CD26; ADABP; ADCP2; DPPIV; TP103; ADCP2; CD26; ADCP-2; DPP IV

DPP4_HUMAN

Human Placenta!!Specific Activity 13U/mg.

766

Greater than 95% as determined by SDS-PAGE.

Each 70ng were lyophilized from 29.1?l containing 2mM Tris-HCl, pH 8.0. Filtered lyophilized (freeze-dried) powder.

Store lyophilized protein at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.

Specifications: The protein was prepared from tissue shown to be non-reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1and 2by FDA required tests. This product is intended for research useonly. Specific Activity: 13U/mg.

Solubility: Add deionized water to prepare a working stock solution of approximately 0.5mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture. Biological Activity: One unit is defined as the amount of enzyme which will hydrolyze 1um of H-Gly-Pro-pNA per 1min at 25 degree C, pH 7.8.

ENZYMES; Enzymes; Peptidase

Description: Dipeptidyl Peptidase-IV was purified from human placenta cells. Introduction: Group IB secretory phospholipase A2 (sPLA2-IB) mediates cell proliferation, cell migration, hormone release and eicosanoid production via its receptor in peripheral tissues. In the CNS, high-affinity binding sites of sPLA2-IB have been documented. sPLA2-IB induced neuronal cell death in a concentrationdependent manner depending on PGD2 metabolites, especially Delta12-PGJ2 that might mediate sPLA2-IB-induced apoptosis. The secretory PLA2 (sPLA2) family, in which 10 isozymes have been identified, consists of lowmolecular weight, Ca2+-requiring secretory enzymes that have been implicated in a number of biological processes, such as modification of eicosanoid generation, inflammation, and host defense.

18765694

NP_001926.2

NM_001935.3

P27487

88,279 Da

Incretin Synthesis, Secretion, And Inactivation Pathway 187170!!Metabolism Of Proteins Pathway 106230!!Peptide Hormone Metabolism Pathway 771603!!Protein Digestion And Absorption Pathway 172847!!Protein Digestion And Absorption Pathway 171868!!Synthesis, Secretion, And Inactivation Of Glucagon-like Peptide-1 (GLP-1) Pathway 187171!!Synthesis, Secretion, And Inactivation Of Glucose-dependent Insulinotropic Polypeptide (GIP) Pathway 187172

The protein encoded by this gene is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. [provided by RefSeq, Jul 2008]

10 ng

205 USD