protein

Bovine Fibroblast Growth Factor-acidic

MBS143477

0.1 mg

2115 USD

Native Protein

Bovine Fibroblast Growth Factor-acidic

Fibroblast Growth Factor-acidic

aFGF Bovine; Fibroblast Growth Factor Acidic Bovine; HBGF-1; ECGF-beta; FIBP; FGFIBP; FIBP-1; ECGF; ECGFA; GLIO703; FGF1; FGF-a

fibroblast growth factor 1; Fibroblast growth factor 1; fibroblast growth factor 1; EDGF II; HBGF-1; aFGF; acidic eye-derived growth factor II; acidic fibroblast growth factor; endothelial cell growth factor beta and alpha chains; endothelial growth factor; fibroblast growth factor, acidic; heparin-binding growth factor 1; prostatropin; fibroblast growth factor 1 (acidic)<; Acidic eye-derived growth factor II; EDGF II; Acidic fibroblast growth factor; aFGF; Endothelial cell growth factor; ECGF; Heparin-binding growth factor 1; HBGF-1; ProstatropinCleaved into the following 2 chains:Endothelial cell growth factor beta; Endothelial cell growth factor alpha

baFGF

FGF1; FGF1; ECGF; FGF-1; AFGF; FGFA; HBGF-1; FGF-1; EDGF II; aFGF; ECGF; HBGF-1

FGF1_BOVIN

Bovine Brain

155

Greater than 90%.

Each 5 ug aFGF were lyophilized from 0.5ml solution containing 1mM sodium phosphate, pH 7 after filtration over a low binding membrane. Sterile Filtered White lyophilized (freeze-dried) powder.

Lyophilized aFGF although stable at room temperature for 2 weeks, should be stored desiccated below -18 degree C. Upon reconstitution aFGF should be stored at 4 degree C between 2-3 weeks and for future use below -18 degree C.Please prevent freeze-thaw cycles.

Solubility: It is recommended to reconstitute the lyophilized aFGF in sterile 50mM Na2HPO4 pH-7, and 0.5% albumin. The Recommended concentration in cell culture: 1-20ng/ml. Biological Activity: Stimulates growth of bovine capillary endothelial cells by 3-5 fold over 5% calf serum at 10-25ng/ml FGF and 0ug/ml heparin.

CYTOKINES AND GROWTH FACTORS; Growth Factors; Fibroblast Growth Factor

Description: Fibroblast Growth Factor-acidic Bovine (FGF-1) purified from Bovine Brain contains a 17 kDa and a 20 kDa polypeptide chain. The 17 kDa peptide is derived from the 20K peptide by restricted proteolysis. (See Jaye et al ). The FGF acidic is purified by proprietary chromatographic techniques. Introduction: Acidic fibroblast growth factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.

27806633

NP_776480.1

NM_174055.2

P03968

17,493 Da

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0.1 mg

2115 USD