product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Thioredoxin-2
catalog :
MBS143453
quantity :
0.02 mg
price :
205 USD
more info or order :
product information
catalog number :
MBS143453
products type :
Recombinant Protein
products full name :
Recombinant Human Thioredoxin-2
products short name :
Thioredoxin-2
products name syn :
TXN2 Human; Thioredoxin-2 Human Recombinant; Thioredoxin mitochondrial; Thioredoxin-2; TXN2; MTRX; TRX2; MT-TRX; TRX-2; TXN-2
other names :
thioredoxin, mitochondrial; Thioredoxin, mitochondrial; thioredoxin, mitochondrial; mitochondrial thioredoxin; thioredoxin-2; thioredoxin 2; Thioredoxin-2
products gene name :
TXN2
other gene names :
TXN2; TXN2; MTRX; TRX2; MT-TRX; TRX2; MTRX; Mt-Trx
uniprot entry name :
THIOM_HUMAN
host :
E Coli
sequence length :
166
sequence :
MTTFNIQDGP DFQDRVVNSE TPVVVDFHAQ WCGPCKILGP RLEKMVAKQH GKVVMAKVDI DDHTDLAIEY EVSAVPTVLA MKNGDVVDKF VGIKDEDQLE AFLKKLIG.
purity :
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
TXN2 protein solution contains 1x PBS pH-7.4. Sterile Filtered colorless solution.
other info2 :
Biological Activity: Specific activity is 3-4 A650/min/mg, obtained by measuring the increase of insulin precipitation in absorbance at 650 nm resulting from the reduction of insulin.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Thioredoxin
products description :
Description: MTRX Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 108 amino acids and having a molecular mass of 11 kDa. Introduction: Thioredoxin-2 is a low molecular weight redox protein. TRX2 contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The TXN2 is involved in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Upon stimulation of Fas, TXN2 mediates denitrosylation of mitochondria-associated caspase-3, a process required for caspase-3 activation, and promoted apoptosis. TRX2 is important at low oxidative stress conditions. MTRX is involved in the regulation of the mitochondrial membrane potential and cell death. Mitochondrial thioredoxin plays an important roles in protection against oxidant-induced apoptosis. Thioredoxin1 and thioredoxin2 have opposed regulatory functions on hypoxia-inducible factor-1alpha.
ncbi gi num :
21361403
ncbi acc num :
NP_036605.2
ncbi gb acc num :
NM_012473.3
uniprot acc num :
Q99757
ncbi mol weight :
18,383 Da
ncbi pathways :
Cellular Responses To Stress Pathway 645258!!Detoxification Of Reactive Oxygen Species Pathway 1127552!!Oxidative Stress Pathway 198916
ncbi summary :
This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq, Jul 2008]
size :
0.02 mg
price :
205 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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