protein

Recombinant Human Ras-Related C3 Botulinum Toxin Substrate 2

MBS143443

0.02 mg

205 USD

Recombinant Protein

Recombinant Human Ras-Related C3 Botulinum Toxin Substrate 2

Ras-Related C3 Botulinum Toxin Substrate 2

RAC2 Human; Ras-Related C3 Botulinum Toxin Substrate 2 Human Recombinant; Ras-related C3 botulinum toxin substrate 2; p21-Rac2; Small G protein; GX; RAC2; HSPC022; EN-7

ras-related C3 botulinum toxin substrate 2; Ras-related C3 botulinum toxin substrate 2; ras-related C3 botulinum toxin substrate 2; Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2); small G protein; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); GX; Small G protein; p21-Rac2

RAC2

RAC2; RAC2; Gx; EN-7; HSPC022; p21-Rac2

RAC2_HUMAN

E Coli

192

MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPRGSHMQA IKCVVVGDGA VGKTCLLISY TTNAFPGEYI PTVFDNYSAN VMVDSKPVNL GLWDTAGQED YDRLRPLSYP QTDVFLICFS LVSPASYENV RAKWFPEVRH HCPSTPIILV GTKLDLRDDK DTIEKLKEKK LAPITYPQGL ALAKEIDSVK YLECSALTQR GLKTVFDEAI RAVLCPQPTR QQKRACSLL.

Greater than 90.0% as determined by SDS-PAGE.

The RAC2 protein solution (1mg/ml) contains 1x PBS pH-7.4. Sterile filtered colorless solution.

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Ras-Related C3 Botulinum Toxin Substrate

Description: Recombinant RAC2 produced in E Coli is a single, non-glycosylated polypeptide chain containing 419 amino acids and having a molecular mass of 47 kDa. RAC2 is fused to GST and purified by conventional chromatography techniques. Introduction: RAC2 is a small signaling G protein/GTPase which is part of the RAS superfamily of small GTP-binding proteins which regulate cell growth, actin cytoskeletal organization, cell proliferation, survival, cell cycle progression, gene transcription rgulation and the activation of protein kinases. RAC2 cycles between an active gtp-bound and inactive gdp-bound state. In active state, RAC2 binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. RAC2 is involved in the regulation of the nadph oxidase.

4506381

NP_002863.1

NM_002872.4

P15153

21,429 Da

Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!Axon Guidance Pathway 83065!!Axon Guidance Pathway 476!!Axon Guidance Pathway 105688!!B Cell Receptor Signaling Pathway 83081!!B Cell Receptor Signaling Pathway 492!!Chemokine Signaling Pathway 99051!!Chemokine Signaling Pathway 96864!!Choline Metabolism In Cancer Pathway 1059539

This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013]

0.02 mg

205 USD