Recombinant Human Fatty Acid Binding Protein-6 | MyBioSource MBS143424 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Fatty Acid Binding Protein-6

catalog :

MBS143424

quantity :

0.005 mg

price :

140 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS143424

products type :

Recombinant Protein

products full name :

Recombinant Human Fatty Acid Binding Protein-6

products short name :

Fatty Acid Binding Protein-6

products name syn :

FABP6 Human; Fatty Acid Binding Protein-6 Human Recombinant; I-BABP; ILBP; I-15P; I-BAP; ILBP3; ILLBP; I-BABP; I-BALB; FABP-6; Gastrotropin; Ileal lipid-binding protein; Intestinal 15 kDa protein; Intestinal bile acid-binding protein; Fatty acid-binding protein 6; FABP6

other names :

gastrotropin isoform 1; Gastrotropin; gastrotropin; GT; ileal bile acid binding protein; ileal lipid-binding protein; illeal lipid-binding protein; intestinal 15 kDa protein; fatty acid binding protein 6, ileal; Fatty acid-binding protein 6; Ileal lipid-binding protein; ILBP; Intestinal 15 kDa protein; I-15P; Intestinal bile acid-binding protein; I-BABP

products gene name :

FABP6

other gene names :

FABP6; FABP6; ILBP; I-15P; I-BAP; ILBP3; ILLBP; I-BABP; I-BALB; ILBP; ILLBP; GT; ILBP; I-15P; I-BABP

uniprot entry name :

FABP6_HUMAN

host :

E Coli

sequence length :

177

sequence :

MAFTGKFEME SEKNYDEFMK LLGISSDVIE KAHNFKIVTE VQQDGQDFTW SQHYYGGHTM TNKFTVGKES NIQTMGGKTF KATVQMEGGK LVVNFPNYHQ TSEIVGDKLV EVSTIGGVTY ERVSKRLA.

purity :

Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

form :

The FABP6 protein solution contains 1xPBS pH-7.4 and 10% Glycerol. Sterile Filtered colorless solution.

products categories :

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; FABP

products description :

Description: FABP6 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 128 amino acids and having a molecular mass of 14 kDa. Introduction: FABP6 also called ileal fatty acid binding protein, is part of the small family of highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 cytosolic protein binds bile acid. FABP6 plays a role in fatty acid uptake, transport, and metabolism. FABP6 stimulates gastric acid and pepsinogen secretion. seems to be able to bind to bile salts and bilirubins.FABP6 expression is restricted in the small intestine to the ileum where it is involved in the enterohepatic circulation of bile acids. Alternate transcription promoters generate 2 transcript variants, encoding a 128 aa and a 177 aa residue protein. Human FABP6 isoform 2 contains 128 amino acid residues and is acetylated on Ala2. FABP6 binds together fatty acids and bile acids and is directly involved in fatty acid transport and metabolism.

ncbi gi num :

94721243

ncbi acc num :

NP_001035532.1

ncbi gb acc num :

NM_001040442.1

uniprot acc num :

P51161

ncbi mol weight :

19,874 Da

ncbi pathways :

Bile Acid And Bile Salt Metabolism Pathway (106144); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Orphan Transporters Pathway (1127546); PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450); Recycling Of Bile Acids And Salts Pathway (106149); Transmembrane Transport Of Small Molecules Pathway (106572)

ncbi summary :

This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

FABP6: Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. 2 isoforms of the human protein are produced by alternative promoter. Protein type: Lipid-binding. Chromosomal Location of Human Ortholog: 5q33.3-q34. Cellular Component: cytoplasm; cytosol. Molecular Function: transporter activity; lipid binding. Biological Process: bile acid and bile salt transport; negative regulation of cell proliferation; bile acid metabolic process; lipid metabolic process; transmembrane transport

size1 :

0.005 mg

price1 :

140 USD

size2 :

0.025 mg

price2 :

205

size3 :

1 mg

price3 :

3490

more info or order :

MyBioSource product webpage