catalog number :
MBS143411
products type :
Recombinant Protein
products full name :
Recombinant Human Calmodulin-2
products short name :
Calmodulin-2
products name syn :
CALM2 Human; Calmodulin-2 Human Recombinant; PHKD; CAMII; PHKD2; Calmodulin-2; CALM2; CALM1 protein; Phosphorylase kinase delta
other names :
CALM1 protein (CALM2 protein) (LP7057 protein); CALM1 protein; CALM1 protein
products gene name :
CALM2
uniprot entry name :
Q96HY3_HUMAN
sequence :
MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAK.
purity :
Greater than 90.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
The CALM2 solution (1mg/ml) contains 20mM Tris-HCl, pH-7.5. Sterile filtered colorless solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Calmodulin
products description :
Description: Recombinant CALM2 produced in E Coli is a single, non-glycosylated polypeptide chain containing 149 amino acids and having a molecular mass of 16 kDa. CALM2 is purified by conventional chromatography techniques. Introduction: Calmodulin-2 acts as an intracellular calcium sensor protein. When the intracellular Ca2+ concentration increases, calmodulin can bind up to four Ca2+, changing its conformation and regulating cellular functions such as activation or inhibition of a large number of enzymes, ion channels, and receptors. P53 protein stimulates CALM2 gene expression in 041 cells. CALM-2 is involved in the processes of Ca(2+)-induced neuronal cell death and the blockage of calmodulin attenuates brain injury after cerebral ischemia. Calmodulin-2 mediates the control of a large number of enzymes and other proteins by ca(2+). among the enzymes to be stimulated by the calmodulin-ca(2+) complex are a number of protein kinases and phosphatases.
ncbi mol weight :
12,876 Da