product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Mouse BH3 Interacting Domain Death Agonist
catalog :
MBS143406
quantity :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS143406
products type :
Recombinant Protein
products full name :
Recombinant Mouse BH3 Interacting Domain Death Agonist
products short name :
BH3 Interacting Domain Death Agonist
products name syn :
BID Mouse; BH3 Interacting Domain Death Agonist Mouse Recombinant; BH3-interacting domain death agonist; p22 BID; BID; FP497; MGC15319; MGC42355
other names :
BH3-interacting domain death agonist; BH3-interacting domain death agonist; BH3-interacting domain death agonist; p22 BID; BH3 interacting domain death agonist; p22 BID; BID
products gene name :
mBID
other gene names :
Bid; Bid; AI875481; AU022477; 2700049M22Rik; BID
uniprot entry name :
BID_MOUSE
host :
E Coli
sequence length :
195
purity :
Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
The Mouse BID protein solution contains 10mM Tris-HCL pH-8, 1mM EDTA and 250mM NaCl. Sterile Filtered colorless liquid formulation.
storage stability :
BID although stable at 15 degree C for 1 week, should be stored desiccated below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; BID
products description :
Description: BID Mouse Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 1-195 amino acids and having a molecular mass of 22 kDa. Introduction: BID is a pro-apoptotic Bcl-2 protein having only the BH3 domain. In reaction to apoptotic signaling, BID interacts with another Bcl-2 family of cell death regulators, called Bax, they form a heterodimer resulting to the insertion of Bax into the outer mitochondrial membrane. Bax induces the opening of the mitochondrial voltage-dependent anion channel which lead to the release of cytochrome c and other pro-apoptotic factors from the mitochondria resulting in activation of caspases. BID is a mediator of mitochondrial damage induced by caspase-8 (CASP8). CASP8 cleaves BID, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. The major proteolytic product p15 BID releasea cytochrome c. Isoform 1, Isoform 2 and Isoform 4 induce ice-like proteases and apoptosis while Isoform 3 does not induce apoptosis.
ncbi gi num :
31542228
ncbi acc num :
NP_031570.2
ncbi gb acc num :
NM_007544.3
uniprot acc num :
P70444
ncbi mol weight :
21,952 Da
ncbi pathways :
Activation And Oligomerization Of BAK Protein Pathway 1111511!!Activation Of BAD And Translocation To Mitochondria Pathway 1111505!!Activation Of BH3-only Proteins Pathway 1111504!!Activation, Myristolyation Of BID And Translocation To Mitochondria Pathway 1111503!!Activation, Translocation And Oligomerization Of BAX Pathway 1111510!!Alzheimer's Disease Pathway 83294!!Alzheimer's Disease Pathway 509!!Amyotrophic Lateral Sclerosis (ALS) Pathway 83296!!Amyotrophic Lateral Sclerosis (ALS) Pathway 511!!Apoptosis Pathway 198339
size :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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