product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Malic Enzyme 2
catalog :
MBS143370
quantity :
1 mg
price :
2365 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS143370
products type :
Recombinant Protein
products full name :
Recombinant Human Malic Enzyme 2
products short name :
Malic Enzyme 2
products name syn :
ME2 Human; Malic Enzyme 2 Human Recombinant; Malic enzyme 2 NAD(+)-dependent mitochondrial; NAD-ME; ODS1; Malate Dehydrogenase; NAD-dependent malic enzyme mitochondrial; pyruvic-malic carboxylase; Malic enzyme 2; EC 1.1.1.38; EC 1.1.1
other names :
NAD-dependent malic enzyme, mitochondrial isoform 2; NAD-dependent malic enzyme, mitochondrial; NAD-dependent malic enzyme, mitochondrial; NAD-ME; malate dehydrogenase; pyruvic-malic carboxylase; malic enzyme 2, NAD(+)-dependent, mitochondrial; Malic enzyme 2
products gene name :
ME2
other gene names :
ME2; ME2; ODS1; NAD-ME
uniprot entry name :
MAOM_HUMAN
host :
E Coli
sequence length :
479
sequence :
KMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGL FISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTAC AGIRPDRCLPVCIDVGTDNIALLKDPFYMGLYQKRDRTQQYDDLIDEFMKAITDRYG RNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVISKPISEH KILFLGAGEAALGIANLIVMSMVENGLSEQEAQKKIWMFDKYGLLVKGRKAKIDSYQ EPFTHSAPESIPDTFEDAVNILKPSTIIGVAGAGRLFTPDVIRAMASINERPVIFALSNPT AQAECTAEEAYTLTEGRCLFASGSPFGPVKLTDGRVFTPGQGNNVYIFPGVALAVILC NTRHISDSVFLEAAKALTSQLTDEELAQGRLYPPLANIQEVSINIAIKVTEYLYANKMAFRYPEPEDKAKYVKERTWRSEYDSLLPDVYEWPESASSPPVITEHHHHHH
MLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPP
KIETQDIQALRFHRNLK
purity :
Greater than 95.0% as determined by(a) Analysis by HPLC. (b) Analysis by SDS-PAGE.
form :
The protein was Lyophilized from a 0.2 um filtered concentrated solution in 20mM Tris, 150mM NaCl, 1mM ?-mercaptoethanol, 1mM EDTA, pH8.0. Sterile Filtered White lyophilized (freeze-dried) powder.
other info2 :
Biological Activity: ME2 activity was assayed spectrophotometrically at 340nm as described in Mandela and Sauer (1975). The standard reaction mixture contained 50mM Tris.HCl, 3mM MnCl2, 5mM malate, 0.12mM NADP+, 2.5mM fumarate, Assay was performed in a Beckman spectrophotometer. The Km value is 1.5 +/-0.6mM.
products categories :
ENZYMES; Enzymes
products description :
Description: ME2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 573 amino acids and having a total molecular mass of 64.4kDa.ME2 is purified by proprietary chromatographic techniques.
ncbi gi num :
270265879
ncbi acc num :
NP_001161807.1
ncbi gb acc num :
NM_001168335.1
uniprot acc num :
P23368
ncbi mol weight :
53,586 Da
ncbi pathways :
Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Pyruvate Metabolism Pathway 82998!!Pyruvate Metabolism Pathway 373
ncbi summary :
This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009]
size :
1 mg
price :
2365 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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