catalog number :
MBS143366
products type :
Recombinant Protein
products full name :
Recombinant Human Lecithin-Cholesterol Acyltransferase
products short name :
[Lecithin-Cholesterol Acyltransferase]
products name syn :
[LCAT Human; Lecithin-Cholesterol Acyltransferase Human Recombinant; Phosphatidylcholine-sterol acyltransferase; Lecithin-cholesterol acyltransferase; Phospholipid-cholesterol acyltransferase; LCAT]
other names :
[phosphatidylcholine-sterol acyltransferase; Phosphatidylcholine-sterol acyltransferase; phosphatidylcholine-sterol acyltransferase; phospholipid-cholesterol acyltransferase; lecithin-cholesterol acyltransferase; Lecithin-cholesterol acyltransferase; Phospholipid-cholesterol acyltransferase]
products gene name :
[LCAT]
other gene names :
[LCAT; LCAT]
uniprot entry name :
LCAT_HUMAN
purity :
Greater than 85.0% as determined by SDS-PAGE.
form :
LCAT protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol
storage stability :
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
other info1 :
Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MGSHMFWLLN VLFPPHTTPK AELSNHTRPV ILVPGCLGNQ LEAKLDKPDV VNWMCYRKTE DFFTIWLDLN MFLPLGVDCW IDNTRVVYNR SSGLVSNAPG VQIRVPGFGK TYSVEYLDSS KLAGYLHTLV QNLVNNGYVR DETVRAAPYD WRLEPGQQEE
YYRKLAGLVE EMHAAYGKPV FLIGHSLGCL HLLYFLLRQP QAWKDRFIDG FISLGAPWGG SIKPMLVLAS GDNQGIPIMS SIKLKEEQRI TTTSPWMFPS RMAWPEDHVF ISTPSFNYTG RDFQRFFADL HFEEGWYMWL QSRDLLAGLP APGVEVYCLY GVGLPTPRTY IYDHGFPYTD
PVGVLYEDGD DTVATRSTEL CGLWQGRQPQ PVHLLPLHGI QHLNMVFSNL TLEHINAILL GAYRQGPPAS PTASPEPPPP E.
other info2 :
Physical Appearance: Sterile filtered colorless solution.
products categories :
ENZYMES; Enzymes; Transferase
products description :
Description: LCAT Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 441 amino acids (25-440) which includes a 25 amino acid His Tag fused at N-terminus and having a total molecular mass of 49.8 kDa. LCAT Human Recombinant is purified by proprietary chromatographic techniques. Introduction: LCAT is an extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. LCAT is a essential enzyme in the extracellular metabolism of plasma lipoproteins.
ncbi acc num :
NP_000220.1
ncbi gb acc num :
NM_000229.1
ncbi pathways :
Glycerophospholipid Metabolism Pathway (82989); Glycerophospholipid Metabolism Pathway (364); HDL-mediated Lipid Transport Pathway (106158); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Statin Pathway (198852)