catalog number :
MBS143362
products type :
Recombinant Protein
products full name :
Recombinant Yeast Glutaredoxin 1
products short name :
Glutaredoxin 1
products name syn :
Thioltransferase, GRX, GLRX1, GRX1, GRX-1, GLRX-1, Glutathione-dependent oxidoreductase 1, Glutaredoxin 1.
other names :
dithiol glutaredoxin GRX1; Glutaredoxin-1; dithiol glutaredoxin GRX1; Glutathione-dependent oxidoreductase 1
products gene name :
GLRX1
other gene names :
GRX1; GRX1
uniprot entry name :
GLRX1_YEAST
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Glutaredoxin solution (1mg/ml) contains 25mM Tris-HCl pH-7.5 & 0.01% Na Azide. Sterile Filtered clear colorless solution.
storage stability :
1 week at 2-10 degree C. For long term store at -20 to -80 degree C.
products categories :
ENZYMES; Enzymes; Gluteradoxin
products description :
Description: Glutaredoxin Saccharamyces cerevisiae Recombinant containing 6x His tag at C-Terminus produced in E Coli is a single, non-glycosylated, Polypeptide chain having a molecular mass of 16 kDa. Introduction: GLRX1 has a glutathione-disulfide oxidoreductase activity in the presence of nadph and glutathione reductase. reduces low molecular weight disulfides and proteins. Glutaredoxin is a glutathione (GSH)-dependent hydrogen donor for ribonucleotide reductase and also catalyzes glutathione-disulfide oxidoreduction reactions in the presence of NADPH and glutathione reductase. GLRX1 is multifunctional enzyme with glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity. The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage.
ncbi acc num :
NP_009895.1
ncbi gb acc num :
NM_001178680.1