Recombinant Human Visfatin, His Tag | MyBioSource MBS143352 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Visfatin, His Tag

catalog :

MBS143352

quantity :

0.005 mg

price :

140 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS143352

products type :

Recombinant Protein

products full name :

Recombinant Human Visfatin, His Tag

products short name :

[Visfatin]

products name syn :

[Visfatin Human, His; Visfatin Recombinant Human, His Tag; PBEF; Pre-B cell colony-enhancing factor; Nicotinamide phosphoribosyltransferase NAmPRTase; Nampt; MGC117256; DKFZP666B131; 1110035O14Rik; Visfatin His]

other names :

[nicotinamide phosphoribosyltransferase; Nicotinamide phosphoribosyltransferase; nicotinamide phosphoribosyltransferase; NAmPRTase; pre-B cell-enhancing factor; pre-B-cell colony enhancing factor 1; pre-B-cell colony-enhancing factor 1; nicotinamide phosphoribosyltransferase; Pre-B-cell colony-enhancing factor 1; Pre-B cell-enhancing factor; Visfatin]

other gene names :

[NAMPT; NAMPT; VF; PBEF; PBEF1; VISFATIN; 1110035O14Rik; PBEF; PBEF1; NAmPRTase; Nampt; Pre-B cell-enhancing factor]

uniprot entry name :

NAMPT_HUMAN

host :

E Coli

sequence length :

491

sequence :

MGSSHHHHHH SSGLVPRGSH MNPAAEAEFN ILLATDSYKV THYKQYPPNT SKVYSYFECR EKKTENSKLR KVKYEETVFY GLQYILNKYL KGKVVTKEKI QEAKDVYKEH FQDDVFNEKG WNYILEKYDG HLPIEIKAVP EGFVIPRGNV LFTVENTDPE CYWLTNWIET ILVQSWYPIT VATNSREQKK ILAKYLLETS GNLDGLEYKL HDFGYRGVSS QETAGIGASA HLVNFKGTDT VAGLALIKKY YGTKDPVPGY SVPAAEHSTI TAWGKDHEKD AFEHIVTQFS SVPVSVVSDS YDIYNACEKI WGEDLRHLIV SRSTQAPLII RPDSGNPLDT VLKVLEILGK KFPVTENSKG YKLLPPYLRV IQGDGVDINT LQEIVEGMKQ KMWSIENIAF GSGGGLLQKL TRDLLNCSFK CSYVVTNGLG INVFKDPVAD PNKRSKKGRL SLHRTPAGNF VTLEEGKGDL EEYGQDLLHT VFKNGKVTKS YSFDEIRKNA QLNIELEAAH H

purity :

Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

form :

Visfatin His tag protein contains 20mM Tris pH-8, 0.1mM DTT & 10% glycerol. Sterile Filtered solution at a concentration of 1mg/ml.

storage stability :

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. Please avoid freeze thaw cycles.

products categories :

CYTOKINES AND GROWTH FACTORS; Cytokines; Visfatin

products description :

Visfatin Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 511 amino acids and having a molecular mass of 57 kDa. The recombinant human Visfatin is fused to His tag at N-Terminus.

ncbi gi num :

5031977

ncbi acc num :

NP_005737.1

ncbi gb acc num :

NM_005746.2

uniprot acc num :

P43490

ncbi pathways :

Adipogenesis Pathway (198832); BMAL1:CLOCK,NPAS2 Activates Circadian Gene Expression Pathway (477138); Circadian Clock Pathway (187173); Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway (906000); Defective BTD Causes Biotidinase Deficiency Pathway (906015); Defective CD320 Causes Methylmalonic Aciduria Pathway (906012); Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway (906001); Defective GIF Causes Intrinsic Factor Deficiency Pathway (906004); Defective HLCS Causes Multiple Carboxylase Deficiency Pathway (906014); Defective LMBRD1 Causes Methylmalonic Aciduria And Homocystinuria Type CblF Pathway (906003)

ncbi summary :

This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10. [provided by RefSeq, Feb 2011]

uniprot summary :

PBEF: an ubiquitous protein originally described as a cytokine which acts on early B-lineage precursor cells. Other reports indicate that PBEF is not a cytokine-like secreted protein but an intracellular protein associated with the cell cycle. Contains a catalytically active nicotinate phosphoribosyltransferase domain, an enzyme involved in nicotinamide adenine dinucleotide (NAD) biosynthesis. Protein type: Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Cell cycle regulation; Transferase; Cytokine; EC 2.4.2.12. Chromosomal Location of Human Ortholog: 7q22.3. Cellular Component: extracellular space; cytosol; nucleus. Molecular Function: protein binding; protein homodimerization activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity; cytokine activity; drug binding; nicotinamide phosphoribosyltransferase activity. Biological Process: circadian rhythm; vitamin metabolic process; positive regulation of smooth muscle cell proliferation; female pregnancy; signal transduction; response to organic cyclic substance; NAD biosynthetic process; cell-cell signaling; nicotinamide metabolic process; NAD metabolic process; positive regulation of cell proliferation; insulin receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; circadian regulation of gene expression; water-soluble vitamin metabolic process; positive regulation of nitric-oxide synthase biosynthetic process

size1 :

0.005 mg

price1 :

140 USD

size2 :

0.025 mg

price2 :

205

size3 :

1 mg

price3 :

4380

more info or order :

MyBioSource product webpage