Somatostatin | MyBioSource MBS143225 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Somatostatin

catalog :

MBS143225

quantity :

1 mg

price :

140 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS143225

products type :

Native Protein

products full name :

Somatostatin

products short name :

Somatostatin

products name syn :

SST; Somatostatin; Growth hormone release-inhibiting factor; SST; SMS; SMST; GHIH

other names :

somatostatin preproprotein; Somatostatin; somatostatin; growth hormone release-inhibiting factor; prepro-somatostatin; somatostatin-14; somatostatin-28; somatostatin; Growth hormone release-inhibiting factorCleaved into the following 2 chains:Somatostatin-28; Somatostatin-14

products gene name :

SST

other gene names :

SST; SST; SMST

uniprot entry name :

SMS_HUMAN

sequence length :

116

sequence :

Ala-Gly-Cys-Lys-Asn-Phe- Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH.

purity :

Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

form :

The protein was lyophilized with no additives. Sterile Filtered White lyophilized (freeze-dried) powder.

storage stability :

Lyophilized SST although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Somatostatin should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

other info2 :

Solubility: It is recommended to reconstitute the lyophilized Somatostatin in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

products categories :

HORMONES; Hormones; Peptide Hormones

products description :

Description: Somatostatin Synthetic is a single, non-glycosylated polypeptide chain containing 14 amino acids, having a molecular mass of 1637.9 Dalton and a Molecular formula of C76H104N18O19S2. The CAS# is 38916-34-6. Introduction: Somatostatin (also known as growth hormone inhibiting hormone (GHIH) or somatotropin release-inhibiting hormone (SRIF) is a peptide hormone that regulates the endocrine systemand affects neurotransmission and cell proliferation via interaction with G-protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. Somatostatin has two active forms produced by alternative cleavage of a single preproprotein: one of 14 amino acids, the other of 28 amino acids.

ncbi gi num :

4507243

ncbi acc num :

NP_001039.1

ncbi gb acc num :

NM_001048.3

uniprot acc num :

P61278

ncbi mol weight :

12,736 Da

ncbi pathways :

Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Gastric Acid Secretion Pathway (154409); Gastric Acid Secretion Pathway (154383); Metabolic Disorders Of Biological Oxidation Enzymes Pathway (1127637); Peptide Ligand-binding Receptors Pathway (106358)

ncbi summary :

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]

uniprot summary :

SST: Somatostatin inhibits the release of somatotropin. Belongs to the somatostatin family. Protein type: Secreted, signal peptide; Secreted; Hormone. Chromosomal Location of Human Ortholog: 3q28. Cellular Component: extracellular space; cell soma; extracellular region. Molecular Function: hormone activity. Biological Process: response to drug; induction of apoptosis by hormones; response to amino acid stimulus; regulation of cell migration; G-protein coupled receptor protein signaling pathway; negative regulation of cell proliferation; synaptic transmission; hyperosmotic response; cell surface receptor linked signal transduction; cell-cell signaling; response to heat; response to steroid hormone stimulus; digestion; response to nutrient

size1 :

1 mg

price1 :

140 USD

size2 :

10 mg

price2 :

205

size3 :

100 mg

price3 :

410

more info or order :

MyBioSource product webpage