catalog number :
MBS143166
products type :
Recombinant Protein
products full name :
Recombinant Treponema pallidum TmpA (Partial)
products short name :
Treponema pallidum TmpA
products name syn :
T.pallidum TmpA partial; Treponema pallidum TmpA (partial) Recombinant; Treponema TmpA
other names :
Treponemal membrane protein A; Treponemal membrane protein A; Antigen TmpA; Membrane protein A
uniprot entry name :
TMPA_TREPH
specificity :
Immunoreactive with sera of Trp. Pallidum infected individuals.
purity :
Protein is >95% pure as determined by 10% PAGE (coomassie staining). Purified by proprietary chromatographic technique.
form :
10mM Tris-HCl pH8.0, 20mM DDT, 1mM EDTA and 8M urea.
storage stability :
T.pallidum TmpA partial although stable at 4 degree C for 1 week, should be stored below -18 degree C. Please prevent freeze thaw cycles.
tested application :
ELISA (EIA), Western ELISA (EIA), Dot Blot (DB), Lateral Flow
app notes :
This protein binds to murine anti-TmpA protein monoclonal antibodies and Treponema pallidum converted human serum polyclonal antibodies in ELISA and Western Elisa. Dot Blots and Lateral Flow immunochromatographic diagnostics test.
products categories :
VIRAL ANTIGENS- TREPONEMA PALLIDUM PROTEINS; Viral Antigens; Treponema
products description :
Description: The E Coli derived 68kDa recombinant protein contains the Trp. Pallidum TmpA immunodominant regions, 23-41 amino acids and 288-325 amino acids. Introduction: Treponema pallidum is a gram-negative spirochaete bacterium and is considered to be metabolically crippled. There are at least four known subspecies: T. pallidum pallidum, T. pallidum pertenue, T. pallidum carateum and T. pallidum endemicum. The helical structure of T. pallidum pallidum allows it to move in a corkscrew motion through viscous mediums such as mucus. Treponema pallidum sub sp. pallidum has one of the smallest bacterial genomes at 1.14 million base pairs (Mb) and has limited metabolic capabilities, reflecting its adaptation through genome reduction to the rich environment of mammalian tissue.
ncbi mol weight :
37,715 Da