Recombinant Human Transforming Growth Factor Beta Induced | MyBioSource MBS143119 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Transforming Growth Factor Beta Induced

catalog :

MBS143119

quantity :

0.005 mg

price :

140 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS143119

products type :

Recombinant Protein

products full name :

Recombinant Human Transforming Growth Factor Beta Induced

products short name :

Transforming Growth Factor Beta Induced

products name syn :

TGFBI Human; Transforming Growth Factor Beta Induced Human Recombinant; Transforming growth factor-beta-induced protein ig-h3; Beta ig-h3; Kerato-epithelin; RGD-containing collagen-associated protein; RGD-CAP; TGFBI; BIGH3; CSD; CDB1; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; CDGG1

other names :

transforming growth factor-beta-induced protein ig-h3; Transforming growth factor-beta-induced protein ig-h3; transforming growth factor-beta-induced protein ig-h3; RGD-CAP; RGD-containing collagen-associated protein; beta ig-h3; kerato-epithelin; transforming growth factor, beta-induced, 68kD; transforming growth factor, beta-induced, 68kDa; Kerato-epithelin; RGD-containing collagen-associated protein; RGD-CAP

products gene name :

TGFBI

other gene names :

TGFBI; TGFBI; CSD; CDB1; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; BIGH3; CDGG1; BIGH3; Beta ig-h3; RGD-CAP

uniprot entry name :

BGH3_HUMAN

host :

E Coli

sequence length :

683

purity :

Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

form :

The TGFBI recombinant Human is formulated 20mM Tris pH-8. Sterile filtered liquid formulation.

storage stability :

Transforming Growth Factor Beta Induced protein Recombinant Human although stable at 4 degree C for 30 days, should be stored below -20 degree C for periods greater than 30 days. Please avoid Freeze/Thaw cycles.

products categories :

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Transforming Growth Factor Beta Induced

products description :

Description: TGFBI Human Recombinant (fourth FAS domain) produced in E Coli is a single, non-glycosylated, polypeptide containing 135 amino acids (502-636) and having a molecular mass of 14.5 kDa. The TGFBI recombinant Human protein is purified by proprietary chromatographic techniques. Introduction: Transforming Growth Factor Beta Induced protein also known as TGFBI is an extracellular matrix protein induced by transforming growth factor (TGF)-beta 1. TGFBI protein is involved in cell growth, cell differentiation, wound healing and cell adhesion. In addition, some missense mutations of TGFBI were identified in families affected with human autosomal dominant corneal dystrophies. TGFBI gene encodes for a 683 amino-acid protein containing an RGD motif and four internal repeated domains which have highly conserved sequences founded in several species (Fasciclin domain).

ncbi gi num :

4507467

ncbi acc num :

NP_000349.1

ncbi gb acc num :

NM_000358.2

uniprot acc num :

Q15582

ncbi mol weight :

74,681 Da

ncbi pathways :

Amyloids Pathway (366238); Disease Pathway (530764)

ncbi summary :

This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008]

uniprot summary :

betaIG-H3: Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation. By TGFB1. Highly expressed in the corneal epithelium. Protein type: Secreted, signal peptide; Cell adhesion; Extracellular matrix; Secreted. Chromosomal Location of Human Ortholog: 5q31. Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; plasma membrane; extracellular region; basement membrane; trans-Golgi network. Molecular Function: collagen binding; integrin binding; protein binding; extracellular matrix binding. Biological Process: cell proliferation; extracellular matrix organization and biogenesis; visual perception; response to stimulus; chondrocyte differentiation; negative regulation of cell adhesion; angiogenesis; cell adhesion. Disease: Corneal Dystrophy, Epithelial Basement Membrane; Corneal Dystrophy, Lattice Type Iiia; Corneal Dystrophy, Avellino Type; Corneal Dystrophy Of Bowman Layer, Type Ii; Corneal Dystrophy, Lattice Type I; Corneal Dystrophy Of Bowman Layer, Type I; Corneal Dystrophy, Groenouw Type I

size1 :

0.005 mg

price1 :

140 USD

size2 :

0.02 mg

price2 :

205

size3 :

1 mg

price3 :

2750

more info or order :

MyBioSource product webpage