catalog number :
MBS143084
products type :
Recombinant Protein
products full name :
Recombinant Human Centrin-3
products short name :
Centrin-3
products name syn :
CETN3 Human; Centrin-3 Human Recombinant; CEN3; CEN-3; CETN-3
other names :
centrin-3 isoform 3; Centrin-3; centrin-3; CDC31 yeast homolog; EF-hand superfamily member; centrin, EF-hand protein, 3 (CDC31 homolog, yeast); centrin, EF-hand protein, 3
products gene name :
CETN3
other gene names :
CETN3; CETN3; CEN3; CDC31; CEN3
uniprot entry name :
CETN3_HUMAN
sequence :
MGSSHHHHHH SSGLVPRGSH MSLALRSELV VDKTKRKKRR ELSEEQKQEI KDAFELFDTD KDEAIDYHEL KVAMRALGFD VKKADVLKILKDYDREATGK ITFEDFNEVV TDWILERDPH EEILKAFKLF DDDDSGKISL RNLRRVAREL GENMSDEELR AMIEEFDKDG DGEINQEEFI AIMTGDI.
purity :
Greater than 95% as determined by SDS-PAGE.
form :
CETN3 Human 0.5mg/ml solution contains 20mM Trsi HCL pH-8, 0.1M NaCl and 10% glycerol. Sterile filtered colorless solution.
storage stability :
CETN3 Human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Centrin
products description :
Description: CETN3 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 187 amino acids (1-167 a.a.) and having a molecular mass of 21.7 kDa. CETN3 protein is fused to a 20 amino acid His-Tag at N-terminus and purified by standard chromatography. Introduction: CETN3 comprises of 4 EF-hand calcium binding domains, and is a part of the centrin protein family. CETN3 protein is widely expressed cytoskeletal components that demonstrate increased expression during cell differentiation. CETN3 takes part in centrosome reproduction.
ncbi acc num :
NP_001284697.1
ncbi gb acc num :
NM_001297768.1
ncbi mol weight :
19,550 Da
ncbi summary :
The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]