protein

Recombinant Human Mammaglobin-A

MBS143067

0.002 mg

140 USD

Recombinant Protein

Recombinant Human Mammaglobin-A

Mammaglobin-A

SCGB2A2 Human; Mammaglobin-A Human Recombinant; Mammaglobin-A; Mammaglobin-1; Secretoglobin family 2A member 2; SCGB2A2; MGB1; UGB2; MGC71974

mammaglobin-A; Mammaglobin-A; mammaglobin-A; mammaglobin 1; secretoglobin, family 2A, member 2; Mammaglobin-1; Secretoglobin family 2A member 2

SCGB2A2

SCGB2A2; SCGB2A2; MGB1; UGB2; MGB1; UGB2

SG2A2_HUMAN

E Coli

93

Greater than 90% as determined by SDS-PAGE.

Filtered (0.4 um) and lyophilized from 0.5 mg/ml in 0.05M phosphate buffer and 0.05M NaCl, pH 7.2. Filtered White lyophilized (freeze-dried) powder.

Store lyophilized protein at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.

Solubility: Add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins

Description: The Recombinant Human SCGB2A2 is produced with N-terminal fusion His Tag. The Recombinant Human SCGB2A2 His-Tagged Fusion Protein, has a molecular weight of 9.88 kDa protein containing 87 amino acid residues of the Human SCGB2A2 including 12 additional amino acid residues His Tag (underlined). Introduction: The mammaglobin gene was first identified using a differential screening approach directed at the isolation of novel, human breast cancer-associated genes. Mammaglobin encodes a 10 kDa glycoprotein and is distantly relaetd to a family of epithelial secretory proteins that includes rat estramustine-binding protein/prostatein and human Clara cell 10 kDa protein (CC10)/uteroglobin. Mammaglobin, a mammary-specific member of the uterglobin family, is known to be overexpressed in human breast cancer. Studies suggest that mammaglobin is one of the first relatively mammary-specific and mammary-sensitive markers (85%). Mammaglobin may be valuable used in a panel with BRST-2 (GCDFP-15) and ER in evaluating tumors of unknown primary sites. SCGB2A2 (the mammaglobin gene) is located on chromosome 11, at locus 11q13. SCGB2A2 is member of the secretoglobin superfamily of which is a group of small dimeric secreted and sometimes glycosylated proteins. Expressed mainly in mucosa, secretoglobins appear to be involved in cell signalling, immune response, chemotaxis, and might also serve as transporters for steroid hormones in humans.

4505169

NP_002402.1

NM_002411.3

Q13296

10,122 Da

SCGB2A2: Belongs to the secretoglobin family. Lipophilin subfamily. 2 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 11q13

0.002 mg

140 USD

0.01 mg

205

1 mg

5015