protein

Recombinant Human C-ets-1 Protein

MBS143054

0.01 mg

610 USD

Recombinant Protein

Recombinant Human C-ets-1 Protein

C-ets-1

ETS1 Human; C-ets-1 Protein Human Recombinant; Protein C-ets-1; ETS-1; p54; ETS1; EWSR2; FLJ10768

protein C-ets-1 isoform 1; Protein C-ets-1; protein C-ets-1; Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1; v-ets avian erythroblastosis virus E2 oncogene homolog 1; v-ets avian erythroblastosis virus E26 oncogene homolog 1; p54

ETS1

ETS1; ETS1; p54; ETS-1; EWSR2; EWSR2

ETS1_HUMAN

E Coli

485

ETS1 protein in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol. Sterile Filtered clear solution.

Store vial at -20 degree C to -80 degree C. When stored at the recommended temperature, this protein is stable for 12 months.Please prevent freeze-thaw cycles.

ELISA (EIA), Inhibition Assays, Western Blot (WB)

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins

Description: ETS1 Human Recombinant (aa 220-442) expressed in E Coli, shows a 48 kDa band on SDS-PAGE (Including GST).The ETS1 is purified by proprietary chromatographic techniques. Introduction: The proto-oncogene c-Ets-1 is a transcription factor known to regulate expression of a number of genes involved in extracellular matrix remodeling, control numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. Ets-1 interacts with the urokinase-type plasminogen activator gene enhancer and with the promoters of stromelysins-1 and collagenase-1 gene which may implicate it in this process. The conserved ETS domain inside these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes.

219689118

NP_001137292.1

NM_001143820.1

P14921

30,860 Da

Angiopoietin Receptor Tie2-mediated Signaling Pathway 137917!!BCR Signaling Pathway 138058!!C-MYB Transcription Factor Network Pathway 138073!!Cellular Senescence Pathway 905991!!Cellular Responses To Stress Pathway 645258!!Dorso-ventral Axis Formation Pathway 114227!!Dorso-ventral Axis Formation Pathway 472!!HIF-1-alpha Transcription Factor Network Pathway 138045!!HIF-2-alpha Transcription Factor Network Pathway 137956!!HTLV-I Infection Pathway 373901

This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

0.01 mg

610 USD