catalog number :
MBS143036
products type :
Recombinant Protein
products full name :
Recombinant Human Exosome Component 8
products short name :
Exosome Component 8
other names :
neural cell adhesion molecule 1 isoform 1; Neural cell adhesion molecule 1; neural cell adhesion molecule 1; antigen recognized by monoclonal antibody 5.1H11; neural cell adhesion molecule, NCAM; neural cell adhesion molecule 1; CD_antigen: CD56
products gene name :
EXOSC8
other gene names :
NCAM1; NCAM1; CD56; NCAM; MSK39; NCAM; N-CAM-1; NCAM-1
uniprot entry name :
NCAM1_HUMAN
form :
CD56 at 100 ug/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol. Physical Appearance: Sterile Filtered clear solution.
products categories :
RECOMBINANT & NATURAL PROTEINS
ncbi acc num :
NP_000606.3
ncbi gb acc num :
NM_000615.6
ncbi mol weight :
40,760 Da
ncbi pathways :
Axon Guidance Pathway (105688); BDNF Signaling Pathway (712093); Cardiac Progenitor Differentiation Pathway (712094); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cytokine Signaling In Immune System Pathway (366171); Developmental Biology Pathway (477129); ECM Proteoglycans Pathway (833812); Extracellular Matrix Organization Pathway (576262); FGF Signaling Pathway (137989)
ncbi summary :
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
uniprot summary :
NCAM1: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. 6 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, GPI anchor; Motility/polarity/chemotaxis; Membrane protein, integral; Cell adhesion. Chromosomal Location of Human Ortholog: 11q23.1. Cellular Component: Golgi membrane; cell surface; membrane; plasma membrane; integral to membrane; external side of plasma membrane. Molecular Function: identical protein binding. Biological Process: axon guidance; extracellular matrix organization and biogenesis; cytokine and chemokine mediated signaling pathway; cell adhesion