catalog number :
MBS143029
products type :
Recombinant Protein
products full name :
Recombinant Human Mortality Factor 4 Like 2
products short name :
Mortality Factor 4 Like 2
products name syn :
MORF4L2 Human; Mortality Factor 4 Like 2 Human Recombinant; Mortality factor 4-like protein 2; MORF-related gene X protein; Protein MSL3-2; Transcription factor-like protein MRGX; MORF4L2; KIAA0026; MRGX; MORFL2
other names :
mortality factor 4-like protein 2; Mortality factor 4-like protein 2; mortality factor 4-like protein 2; MORF-related gene X protein; MSL3-2 protein; protein MSL3-2; transcription factor-like protein MRGX; mortality factor 4 like 2; MORF-related gene X protein; Protein MSL3-2; Transcription factor-like protein MRGX
products gene name :
MORF4L2
other gene names :
MORF4L2; MORF4L2; MRGX; MORFL2; KIAA0026; MRGX
uniprot entry name :
MO4L2_HUMAN
purity :
Greater than 90.0% as determined by SDS-PAGE.
form :
The MORF4L2 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol and 1mM DTT. Sterile Filtered colorless solution.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Mortality Factor
products description :
Description: MORF4L2 produced in E Coli is a single, non-glycosylated polypeptide chain containing 308 amino acids (1-288 a.a.) and having a molecular mass of 34.4kDa (Molecular weight on SDS-PAGE will appear higher).MORF4L2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Introduction: MORF4L2 belongs to the mortality factor (MORF) family of transcriptional regulator which is involved in cell growth, regulation and senescence. MORF4L2 localizes to the nucleus, and it has a protein kinase C phosphorylation site as well as a tyrosine phosphorylation site. MORF4L2 interacts with the Rb tumor suppressor through its helix-loop-helix and leucine zipper regions. Furthermore, MORF4L2 has histone deacetylase activity and can either repress or promote the activity of the B-Myb promoter depending on the tissue.
ncbi acc num :
NP_001135890.1
ncbi gb acc num :
NM_001142418.1
ncbi mol weight :
32,308 Da
ncbi pathways :
Chromatin Modifying Enzymes Pathway 1127682!!Chromatin Organization Pathway 1127681!!HATs Acetylate Histones Pathway 1127683