catalog number :
MBS143022
products type :
Recombinant Protein
products full name :
Recombinant Human CD2, GST Tag
products short name :
CD2
products name syn :
CD2 Human, GST; CD2 Human Recombinant, GST Tag; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; LFA-2; LFA-3 receptor; Erythrocyte receptor; Rosette receptor; CD2 antigen; CD2; T11; SRBC; CD2 GST
other names :
T-cell surface antigen CD2; T-cell surface antigen CD2; T-cell surface antigen CD2; CD2 antigen (p50), sheep red blood cell receptor; LFA-3 receptor; T-cell surface antigen T11/Leu-5; erythrocyte receptor; lymphocyte-function antigen-2; rosette receptor; CD2 molecule; Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD_antigen: CD2
other gene names :
CD2; CD2; T11; SRBC; LFA-2; SRBC
uniprot entry name :
CD2_HUMAN
form :
CD2 at 100 ug/ml in 50mM Tris-HCl pH7.5 and 10Mm L-glutathione (reduced). Sterile Filtered clear solution.
storage stability :
Store vial at -20 degree C to -80 degree C. When stored at the recommended temperature, this protein is stable for 12 months.Please prevent freeze-thaw cycles.
tested application :
ELISA (EIA), Inhibition Assays, Western Blot (WB)
products categories :
RECOMBINANT & NATURAL PROTEINS; CD Antigens
products description :
Description: CD2 Human Recombinant (aa 25-209) expressed in E Coli, shows a 46 kDa band on SDS-PAGE.The CD2 is purified by proprietary chromatographic techniques. Introduction: CD2 which is also known as E-rosette receptor, T11 and lymphocytefunction antigen-2 (LFA-2) is expressed on T cells, thymocytes, and subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, human CD58 (LFA-3), and CD15s (Sialyl Lewis X). p56lck, p59fyn, CD3eta and CD3epsilon are tyrosine-phosphorylated after CD2 stimulation. CD2 plays a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.
ncbi acc num :
NP_001758.2
ncbi gb acc num :
NM_001767.3
ncbi mol weight :
39,448 Da
ncbi pathways :
Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480!!Cell Surface Interactions At The Vascular Wall Pathway 106062!!Hematopoietic Cell Lineage Pathway 83078!!Hematopoietic Cell Lineage Pathway 489!!Hemostasis Pathway 106028
ncbi summary :
CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it.[supplied by OMIM, Jul 2010]