protein

Recombinant Human BP-1

MBS143017

0.002 mg

265 USD

Recombinant Protein

Recombinant Human BP-1

BP-1

BP-1 Human; BP-1 Human Recombinant; Homeobox protein DLX-4; DLX-7; DLX-8; Beta protein 1; BP1; DLX7; DLX8; DLX9; DLX4

homeobox protein DLX-4 isoform b; Homeobox protein DLX-4; homeobox protein DLX-4; beta protein 1; distal-less homeo box 7; distal-less homeo box 9; homeobox protein DLX-7; homeobox protein DLX-8; distal-less homeobox 4; Beta protein 1; Homeobox protein DLX-7; Homeobox protein DLX-8

BP-1

DLX4; DLX4; BP1; DLX7; DLX8; DLX9; BP1; DLX7; DLX8; DLX9

DLX4_HUMAN

E Coli

168

BP-1 protein in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol. Sterile Filtered clear solution.

100ug/ml

Store vial at -20 degree C to -80 degree C. When stored at the recommended temperature, this protein is stable for 12 months.Please prevent freeze-thaw cycles.

ELISA (EIA), Inhibition Assays, Western Blot (WB)

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins

Description: BP-1 Human Recombinant (aa 103-168) expressed in E Coli, shows a 35 kDa band on SDS-PAGE.The BP-1 is purified by proprietary chromatographic techniques. Introduction: BP-1 gene, a member of the DLX homeobox gene family, is overexpressed in 80% of breast cancer patients, and thus represents a potential new target for diagnosis and treatment.Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly (Drosophila). The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.

20143960

NP_001925.2

NM_001934.3

Q92988

12,713 Da

Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function. [provided by RefSeq, Jul 2008]

DLX4: May play a role in determining the production of hemoglobin S. May act as a repressor. Belongs to the distal-less homeobox family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription factor; DNA-binding. Chromosomal Location of Human Ortholog: 17q21.33. Cellular Component: nucleus. Molecular Function: protein binding; sequence-specific DNA binding; transcription factor activity. Biological Process: regulation of transcription, DNA-dependent; multicellular organismal development; negative regulation of transcription from RNA polymerase II promoter

0.002 mg

265 USD

0.005 mg

365

0.01 mg

610