catalog number :
MBS142993
products type :
Native Protein
products full name :
Human Prothrombin Complex
products short name :
Prothrombin Complex
products name syn :
PCC; Prothrombin Complex; PCC; Prothrombin Complex; Prothrombin
other names :
Prothrombin; Prothrombin; Prothrombin
other gene names :
prothrombin
uniprot entry name :
Q16505_HUMAN
form :
Lyophilized Powder from 0.1M sodium chloride and 10mM sodium citrate buffer. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Prothrombin-Complex although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Prothrombin-Complex should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Prothrombin Complex in sterile 18M Omega -cm H2O.
products categories :
RECOMBINANT & NATURAL PROTEINS; Natural Proteins; Coagulation Factors
products description :
Description: Prothrombin complex is a double virusinactivated concentrate, containing equal concentrations of Factors II, VIII, IX, X and Heparin. Introduction: Prothrombin Complex Concentrate (PCC) is a combination of several blood clotting factors II, VII, IX and X. PCC is used in the treatment of the congenital bleeding disorders associated with Factors II, VII, IX, and X deficiencies. PCC reverses the effect of warfarin (a coumarin anti-coagulant) and is used in cases of significant bleeding in patients with a coagulopathy, for example, gastrointestinal haemorrhage or intracranial haemorrhage. The PCC is also extensively used in treating acquired coagulation abnormalities secondary to vitamin K deficiency, warfarin ingestion, and various types of liver disease. Hepatitis, anaphylaxis and thrombosis have been reported as complications of prothrombin complex concentrates administration.
ncbi mol weight :
7,273 Da