Recombinant Human Fatty Acid Binding Protein-5 | MyBioSource MBS142972 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Fatty Acid Binding Protein-5

catalog :

MBS142972

quantity :

0.002 mg

price :

140 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS142972

products type :

Recombinant Protein

products full name :

Recombinant Human Fatty Acid Binding Protein-5

products short name :

Fatty Acid Binding Protein-5

products name syn :

FABP5 Human; Epidermal Fatty Acid Binding Protein Human Recombinant; Fatty acid-binding protein epidermal; E-FABP; Fatty acid-binding protein 5; Psoriasis-associated fatty acid-binding protein homolog; PA-FABP; FABP5; EFABP; PAFABP

other names :

fatty acid-binding protein, epidermal; Fatty acid-binding protein, epidermal; fatty acid-binding protein, epidermal; epidermal-type fatty acid-binding protein; psoriasis-associated fatty acid-binding protein homolog; fatty acid binding protein 5 (psoriasis-associated); Epidermal-type fatty acid-binding protein; E-FABP; Fatty acid-binding protein 5; Psoriasis-associated fatty acid-binding protein homolog; PA-FABP

products gene name :

FABP5

other gene names :

FABP5; FABP5; EFABP; KFABP; E-FABP; PAFABP; PA-FABP; E-FABP; PA-FABP

uniprot entry name :

FABP5_HUMAN

host :

E Coli

sequence length :

135

specificity :

The amino acid sequence of the recombinant human FABP5 is 100% homologous to the amino acid sequence of the human FABP-5.

purity :

Greater than 90% as determined by SDS PAGE. Two-step procedure using size exclusion chromatography before and after refolding.

form :

Sterile filtered and lyophilized from 0.5 mg/ml in phosphate buffered saline. Sterile Filtered lyophilized (freeze-dried) powder.

storage stability :

Store lyophilized protein at -20 degree C. Aliquot the product after reconstitution to avoid freeze-thaw cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.

other info2 :

Solubility: Add 0.2 ml of dH20 and let the lyophilized pellet dissolve completely.

products categories :

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; FABP

products description :

Description: Recombinant Human Epidermal Fatty Acid Binding Protein (FABP-5) is a monodimeric, non-glycosylated, polypeptide chain containing 135 amino acids and having a total molecular mass of 15200 Daltons. Introduction: Human Fatty Epidermal Acid Binding Protein FABP also called FABP-5 is a 15 kD member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to bind fatty acids and related compounds (bile acids or retinoids). In an internal cavity. The fatty acid binding proteins aP2 (fatty acid binding protein [FABP]-4) and mal1 (EFABP) are closely related and both are expressed in adipocytes. Absence of EFABP/mal1 resulted in increased systemic insulin sensitivity in two models of obesity and insulin resistance. Adipocytes isolated from mal1-deficient mice also exhibited enhanced insulin-stimulated glucose transport capacity. In contrast, mice expressing high levels of mal1 in adipose tissue display reduced systematic insulin activity.

ncbi gi num :

4557581

ncbi acc num :

NP_001435.1

ncbi gb acc num :

NM_001444.2

uniprot acc num :

Q01469

ncbi mol weight :

15,164 Da

ncbi pathways :

PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450); Signal Transduction Pathway (477114); Signaling By Retinoic Acid Pathway (1127533)

ncbi summary :

This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011]

uniprot summary :

FABP5: High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Protein type: Lipid-binding. Chromosomal Location of Human Ortholog: 8q21.13. Cellular Component: nucleoplasm; cytoplasm; cytosol. Molecular Function: protein binding; transporter activity; lipid binding; fatty acid binding. Biological Process: epidermis development; phosphatidylcholine biosynthetic process; glucose metabolic process; glucose transport; lipid metabolic process

size1 :

0.002 mg

price1 :

140 USD

size2 :

0.01 mg

price2 :

205

size3 :

1 mg

price3 :

4140

more info or order :

MyBioSource product webpage