catalog number :
MBS142967
products type :
Recombinant Protein
products full name :
Recombinant Mouse Bax
products short name :
Bax
products name syn :
Bax Mouse; Bax Mouse Recombinant; Apoptosis regulator BAX membrane isoform alpha; Bax; Bcl2-associated X protein
other names :
apoptosis regulator BAX; Apoptosis regulator BAX; apoptosis regulator BAX; BCL2-associated X protein
products gene name :
mBAX
other gene names :
Bax; Bax
uniprot entry name :
BAX_MOUSE
purity :
Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
The protein contains 10mM Tris-HCL pH-8, 1mM EDTA and 250mM NaCl. Sterile Filtered colorless solution.
storage stability :
Mouse Bax although stable at 12 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze-thaw cycles.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Bax
products description :
Description: Bax Mouse Recombinant amino acid 38-171 produced in E Coli is a single, non-glycosylated polypeptide chain. The Mouse Bax is purified by proprietary chromatographic techniques. Introduction: Bcl-2associated X protein (Bax) belongs to the Bcl-2 protein family. Bax is a pro-apoptotic Bcl-2 protein containing BH1, BH2 and BH3 domains. Bax accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor bcl2 or its adenovirus homolog e1b 19k protein. Bax induces the release of cytochrome c, activation of casp3, and thereby apoptosis. Bax is expressed in a wide variety of tissues, with highest levels in the testis and ovary. Tumor suppressor protein p53 upregulates the expression of BAX. Bax has been shown to be involved in p53-mediated apoptosis.
ncbi acc num :
NP_031553.1
ncbi gb acc num :
NM_007527.3
ncbi pathways :
Activation, Translocation And Oligomerization Of BAX Pathway (1111510); Amyotrophic Lateral Sclerosis (ALS) Pathway (83296); Amyotrophic Lateral Sclerosis (ALS) Pathway (511); Apoptosis Pathway (198339); Apoptosis Pathway (83257); Apoptosis Pathway (470); Apoptosis Pathway (1111498); Apoptosis Signaling Pathway (522973); B Cell Receptor Signaling Pathway (198285); Colorectal Cancer Pathway (83299)