catalog number :
MBS142965
products type :
Native Protein
products full name :
Dog Calsequestrin-2
products short name :
Calsequestrin-2
products name syn :
CASQ2 Dog; Calsequestrin-2 Dog; Calsequestrin-2; Calsequestrin cardiac muscle isoform; CASQ2; CSQ
other names :
Calsequestrin-2; Calsequestrin-2; calsequestrin-2; calsequestrin 2 (cardiac muscle); Calsequestrin-2; calsequestrin, cardiac muscle isoform; cardiac calsequestrin; Calsequestrin, cardiac muscle isoform
products gene name :
dCASQ2
other gene names :
CASQ2; CASQ2; CAL
uniprot entry name :
CASQ2_CANFA
purity :
Greater than 90% as determined by SDS-PAGE.
form :
The protein was lyophilized from a concentrated solution (1mg/ml) containing 10mM Tris-HCl and 1mM EGTA. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized CASQ2 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution CASQ2 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized CASQ2 in sterile 18M-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
products categories :
RECOMBINANT & NATURAL PROTEINS; Natural Proteins
products description :
Description: Calsequestrin is the major calcium storage protein of the sarcoplasmic reticulum. Intraluminar Ca2+ binds to calsequestrin during diastole to prevent Ca2+ precipitation and to lower its free ionic concentration to facilitate efficient storage. During systole, Calsequestrin coordinately releases ~40- 50 Ca2+ ions per molecule for each contraction-relaxation cycle by an uncertain mechanism. Calsequestrin has been shown to be of major importance in the regulation of cardiac excitation-contraction coupling.
ncbi mol weight :
47,417 Da
ncbi pathways :
Calcium Regulation In The Cardiac Cell Pathway 198600