product summary
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company name :
MyBioSource
product type :
protein
product name :
Cyclosporin-A
catalog :
MBS142963
quantity :
1 g
price :
140 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142963
products type :
Native Protein
products full name :
Cyclosporin-A
products short name :
Cyclosporin-A
products name syn :
Cyclosporin A; Cyclosporin-A; Cyclosporin-A
host :
Beauveria Nlyea
purity :
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Mass Spectral Anaylsis {MALDI-TOF exhibits correct Mw}.
form :
The Cyclosporin-A was lyophilized from a concentrated (1mg/ml) solution with no additives. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Cyclosporin A although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Cyclosporin A should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Cyclosporin-A in Ethanol.
products categories :
RECOMBINANT & NATURAL PROTEINS; Natural Proteins
products description :
Description: Cyclosporin is a cyclic polypeptide immunosuppressant agent consisting of 11 amino acids and having a molecular weight of 1202.64. It is produced as a metabolite by the fungus species Beauveria nlyea. Chemically, cyclosporin is designated as [R-[R*,R*-(E)]]-cyclic(L-alanyl-D- alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N, 4-dimethyl-L-2-amino-6-octenoyl-L-?-amino-butyryl- N-methylglycyl-N- methyl-L-leucyl-L-valyl-N-methyl-L-leucyl). Molecular Formula: C62H111N11O12. Introduction: Cyclosporin A is a noncytotoxic, natural, 11 amino acid cyclic peptide used clinically as an immunosuppressant for the treatment of autoimmune and inflammatory disorders and to prevent organ rejection after transplantation. Cyclosporin acts chiefly by inhibiting T lymphocyte function, which is vital for the propagation of inflammation. Cyclosporin A does not suppress the activity of other hematopoietic cells, does not cause bone marrow suppression and has a rapid onset of action as opposed to other immunosuppressive agents. Nevertheless, Cyclosporin A -induced nephrotoxicity remains an important clinical problem, and oxidative stress has been implicated as a potential responsible mechanism.
size1 :
1 g
price1 :
140 USD
size2 :
4 g
price2 :
205
size3 :
100 g
price3 :
1220
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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