protein

Human Alpha Fetoprotein

MBS142961

0.005 mg

140 USD

Native Protein

Human Alpha Fetoprotein

Alpha Fetoprotein

AFP Human; Alpha-Fetoprotein Human; Alpha-fetoprotein; Alpha-fetoglobulin; Alpha-1-fetoprotein; AFP; FETA; HPAFP

alpha-fetoprotein; Alpha-fetoprotein; alpha-fetoprotein; alpha-1-fetoprotein; alpha-fetoglobulin; alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin

AFP

AFP; AFP; AFPD; FETA; HPAFP; HPAFP

FETA_HUMAN

Human cord serum

609

Alpha Fetoprotein protein at 2.5mg/ml 0.1M PBS buffer pH 7.4 containing 0.1% NaN3. Sterile Filtered clear solution.

2ug/0.8ul

Store vial at -20 degree C to -80 degree C. When stored at the recommended temperature, this protein is stable for 12 months.Please prevent freeze-thaw cycles.

Characterization: On SDS-PAGE commassie blue stained gel, the purified protein shows a band at 70kDa.

RECOMBINANT & NATURAL PROTEINS; Natural Proteins

Description: Human alpha-fetoprotein purified from human cord serum. Introduction: AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

4501989

NP_001125.1

NM_001134.2

P02771

68,678 Da

Direct P53 Effectors Pathway (137939); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Glucocorticoid Receptor Regulatory Network Pathway (138014); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388)

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]

AFP: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. Dimeric and trimeric forms have been found in addition to the monomeric form. Plasma. Synthesized by the fetal liver and yolk sac. Belongs to the ALB/AFP/VDB family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: extracellular space; cytoplasm. Molecular Function: metal ion binding. Biological Process: transport; progesterone metabolic process; ovulation from ovarian follicle. Disease: Alpha-fetoprotein Deficiency; Alpha-fetoprotein, Hereditary Persistence Of

0.005 mg

140 USD

0.025 mg

205

1 mg

2170