protein

Recombinant Human Apolipoprotein-H, Sf9

MBS142943

0.005 mg

140 USD

Recombinant Protein

Recombinant Human Apolipoprotein-H, Sf9

Apolipoprotein-H

APOH Human, sf9; Apolipoprotein-H Human Recombinant, Sf9; Beta-2-glycoprotein 1; Beta-2-glycoprotein I; Apolipoprotein H; Apo-H; B2GPI; Beta(2)GPI; Activated protein C-binding protein; APC inhibitor; Anticardiolipin cofactor; APOH; B2G1; BG; B2GP-1; B2 Glycoprotein-I; APOH sf9

beta-2-glycoprotein 1; Beta-2-glycoprotein 1; beta-2-glycoprotein 1; APC inhibitor; B2GPI; activated protein C-binding protein; anticardiolipin cofactor; apo-H; beta(2)GPI; apolipoprotein H (beta-2-glycoprotein I); APC inhibitor; Activated protein C-binding protein; Anticardiolipin cofactor; Apolipoprotein H; Apo-H; Beta-2-glycoprotein I; B2GPI; Beta(2)GPI

APOH

APOH; APOH; BG; B2G1; B2GP1; B2G1; Apo-H; B2GPI; Beta(2)GPI

APOH_HUMAN

Sf9 Insect Cells

345

Greater than 95% as determined by SDS-PAGE.

APOH (0.95mg/ml) is supplied in 16mM HEPES buffer pH-7.2, 200mM NaCl and 20% glycerol. Sterile Filtered clear solution.

Coating Concentration: 0.5-1 ug/ml (depending on the type of ELISA plate and coating buffer).Suitable for biotinylation and iodination.

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. Avoid multiple freeze-thaw cycles.

RECOMBINANT & NATURAL PROTEINS; Cytokines; Apolipoprotein

Description: Apolipoprotein-H Human Recombinant produced in SF9 is a glycosylated, polypeptide chain containing 326 amino acids and having a molecular mass of 38,200 Dalton (excluding glycosylation), 45kDa total mass. APOH is expressed with a -6xHis tag and purified by proprietary chromatographic techniques. Introduction: Apolipoprotein H (APOH) attaches to numerous kinds of negatively charged substances for instance heparin, phospholipids, and dextran sulfate. APOH prevents activation of the intrinsic blood coagulation cascade by attaching to phospholipids on the surface of damaged cells. APOH expressed by the liver and secreted in the plasma.

153266841

NP_000033.2

NM_000042.2

P02749

38,298 Da

Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections. [provided by RefSeq, Jul 2008]

APOH: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. Protein type: Lipid-binding; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 17q24.2. Cellular Component: extracellular matrix; extracellular space; chylomicron; cell surface. Molecular Function: heparin binding; identical protein binding; protein binding; phospholipid binding; glycoprotein binding; lipid binding. Biological Process: negative regulation of myeloid cell apoptosis; negative regulation of angiogenesis; triacylglycerol metabolic process; negative regulation of fibrinolysis; positive regulation of blood coagulation; negative regulation of endothelial cell proliferation; positive regulation of lipoprotein lipase activity; negative regulation of blood coagulation; triacylglycerol transport; blood coagulation, intrinsic pathway; plasminogen activation; regulation of fibrinolysis

0.005 mg

140 USD

0.02 mg

205

1 mg

2750