catalog number :
MBS142939
products type :
Recombinant Protein
products full name :
Recombinant Human S100 Calcium Binding Protein A10
products short name :
S100 Calcium Binding Protein A10
products name syn :
S100A10 Human; S100 Calcium Binding Protein A10 Human Recombinant; Protein S100-A10; S100 calcium-binding protein A10; Calpactin-1 light chain; Calpactin I light chain; p10 protein; p11; Cellular ligand of annexin II; S100A10; ANX2LG; CAL1L; CLP11; 42C; p10; GP11; ANX2L; Ca[1]; MGC111133
other names :
protein S100-A10; Protein S100-A10; protein S100-A10; S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); S100 calcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); annexin II tetramer (AIIt) p11 subunit; calpactin I light chain; calpactin-1 light chain; cellular ligand of annexin II; S100 calcium binding protein A10; Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; S100 calcium-binding protein A10; p10 protein; p11
products gene name :
S100A10
other gene names :
S100A10; S100A10; 42C; P11; p10; GP11; ANX2L; CAL1L; CLP11; Ca[1]; ANX2LG; ANX2LG; CAL1L; CLP11
uniprot entry name :
S10AA_HUMAN
purity :
Greater than 95% as determined by SDS-PAGE.2 bands on Western blot at 15.3 and 30.6 kDa, respectively representing monomeric and dimeric form.
form :
S100-A10 is supplied in 1xPBS and 50% Glycerol.
concentration :
0.5 mg/ml
storage stability :
Store at 4 degree C if entire vial will be used within 1-2 weeks. Store, frozen at -20 degree C for longer periods of time. Avoid multiple freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
app notes :
S100A10 can be used directly as a positive control in Western blotting, ELISA, immunoprecipitation and other immunological experiments. The biological activity of this product has not yet been tested.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Calcium Binding Protein
products description :
Description: S100A10 Human Recombinant also called Calpactin light chain is expressed in E Coli having a molecular weight of 15.3kDa fused to an amino terminal hexahistidine tag. Introduction: S100A10 is a member of the S100 family of proteins contains two EF-hand calcium-binding motifs and is thought to be involved in the regulation of a number of cellular processes including cell cycle progression and differentiation. S100 proteins are localized either in the cytoplasm or the nucleus of a wide range of cells. There are at least 13 members in the S100 gene family, which are located as a cluster on chromosome 1q21. S100A10 may function in exocytosis and endocytosis.
ncbi acc num :
NP_002957.1
ncbi gb acc num :
NM_002966.2
ncbi mol weight :
11,203 Da
ncbi pathways :
Dissolution Of Fibrin Clot Pathway (106061); Hemostasis Pathway (106028); Orphan Transporters Pathway (1127546); Prostaglandin Synthesis And Regulation Pathway (198912); Transmembrane Transport Of Small Molecules Pathway (106572)
ncbi summary :
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008]
uniprot summary :
S100A10: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase. Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with SCN10A. Belongs to the S-100 family. Protein type: Calcium-binding. Chromosomal Location of Human Ortholog: 1q21. Cellular Component: extrinsic to plasma membrane; lipid raft. Molecular Function: protein binding; protein homodimerization activity; calcium ion binding; lipid binding. Biological Process: positive regulation of focal adhesion formation; positive regulation of stress fiber formation; protein heterotetramerization; positive regulation of binding; lipid raft formation; membrane budding