protein

Recombinant Human Non-Muscle Myosin-II Regulatory Light Chain

MBS142921

0.002 mg

140 USD

Recombinant Protein

Recombinant Human Non-Muscle Myosin-II Regulatory Light Chain

Non-Muscle Myosin-II Regulatory Light Chain

NMM Human; Non-Muscle Myosin-II Regulatory Light Chain Human Recombinant; Non-Muscle Myosin-II Regulatory Light Chain; NMM

NMM

E Coli

MSSKKAKTKT TKKRPQRATS NVFAMFDQSQ IQEFKEAFNM IDQNRDGFID KEDLHDMLAS LGKNPTDAYL DAMMNEAPGP INFTMFLTMF GEKLNGTDPE DVIRNAFACF DEEATGTIQE DYLRELLTTM GDRFTDEEVD ELYREAPIDK KGNFNYIEFT RILKHGAKDK DD.

Greater than 95.0% as determined by SDS-PAGE.

NMM protein at 0.2mg/ml in 20mM HEPES-KOH, pH7, 50mM NaCl, 1mM EDTA and 1mM DTT. Sterile Filtered clear solution.

Store vial at -20 degree C to -80 degree C. When stored at the recommended temperature, this protein is stable for 12 months.Please prevent freeze-thaw cycles.

Activity: Assayed for phosphorilation by MLCK.

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Myosin Light Chain

Description: Non-Muscle Myosin-II Regulatory Light Chain Human Recombinant full length expressed in E Coli.The NMM is purified by proprietary chromatographic techniques. Introduction: Non muscle Myosins are required for cytokinesis at the end of cell division, when a contractile ring near the plasmalemma divides the cytoplasm of the daughter cells. They are involved in cytoplasmic streaming movements in tissues, and especially in activation of motile cells such as fibroblasts and macrophages. Activation of non-muscle myosin-II is achieved by phosphorylation of Ser33 in the motif KKRPQRATSN by a dedicated, Ca +2 Calmodulin regulated light chain kinase (MLCK).

0.002 mg

140 USD

0.01 mg

205

1 mg

4480