protein

Human Serum Albumin

MBS142909

100 mg

140 USD

Native Protein

Human Serum Albumin

Serum Albumin

HSA; Human Serum Albumin; Serum albumin; ALB; PRO0883; PRO0903; PRO1341; DKFZp779N1935; GIG20; GIG42; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696; SA; HSA

serum albumin preproprotein; Serum albumin; serum albumin; albumin (32 AA); albumin (AA 34); cell growth inhibiting protein 42; growth-inhibiting protein 20; albumin

HSA

ALB; ALB; FDAH; ANALBA; PRO0883; PRO0903; PRO1341

ALBU_HUMAN

Human Serum

609

Greater than 99.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

0.25gr/ml solution containing no additives. Sterile Filtered clear orange solution.

Human Serum Albumin although stable at room temperature for 2 weeks should be stored at 4 degree C.

Formulation of Protein Therapeutics Cell Storage: Cryopreservation Vaccine formulation and manufacturing Development of mammalian cell cultures Infertility treatments Coating for medical devices Drug delivery In vivo diagnostics.

RECOMBINANT & NATURAL PROTEINS; Natural Proteins; Albumin

Description: Human Serum Albumin contains 584 amino acid residues derived from the prototypical human serum albumin sequence. Suitable for use in biochemical, excipient (an inert substance used as a diluent or vehicle for a drug), culture media and chromatographic applications. Introduction: Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. The human albumin gene is 16,961 nucleotides long from the putative 'cap' site to the first poly (A) addition site. It is split into 15 exons which are symmetrically placed within the 3 domains that are thought to have arisen by triplication of a single primordial domain. HSA is widely used to stabilize blood volume generally from donors but the fear of contamination such as HIV & Hepatitis has enticed great interest in the recombinant form which is identical to the natural blood.

4502027

NP_000468.1

NM_000477.5

P02768

45,160 Da

Bile Acid And Bile Salt Metabolism Pathway (106144); Binding And Uptake Of Ligands By Scavenger Receptors Pathway (771599); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); HDL-mediated Lipid Transport Pathway (106158); Hemostasis Pathway (106028); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Platelet Activation, Signaling And Aggregation Pathway (106034)

Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008]

albumin: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Plasma. Belongs to the ALB/AFP/VDB family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide; Carrier. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: extracellular space; protein complex; extracellular region; basement membrane; nucleus. Molecular Function: antioxidant activity; toxin binding; protein binding; enzyme binding; copper ion binding; DNA binding; zinc ion binding; chaperone binding; drug binding; oxygen binding; fatty acid binding; pyridoxal phosphate binding. Biological Process: receptor-mediated endocytosis; platelet activation; sodium-independent organic anion transport; bile acid metabolic process; maintenance of mitochondrion localization; hemolysis by symbiont of host red blood cells; lipoprotein metabolic process; cellular response to starvation; response to organic substance; response to mercury ion; bile acid and bile salt transport; retinal homeostasis; platelet degranulation; transport; negative regulation of programmed cell death; blood coagulation; transmembrane transport; positive regulation of circadian sleep/wake cycle, non-REM sleep; response to nutrient; negative regulation of apoptosis. Disease: Analbuminemia; Hyperthyroxinemia, Familial Dysalbuminemic

100 mg

140 USD

500 mg

205

5 g

790