protein

Recombinant Rat Receptor Associated Protein

MBS142907

0.005 mg

140 USD

Recombinant Protein

Recombinant Rat Receptor Associated Protein

Receptor Associated

RAP Rat; Receptor Associated Protein Rat Recombinant; Receptor Associated Protein; RAP

protein RAP; At2g31890/F20M17.7; protein RAP; At2g31890/F20M17.7

rRAP

RAP; RAP; ATRAP; F20M17.7; F20M17_7; RAP

Q8VZE7_ARATH

E Coli

671

Greater than 95.0% as determined by SDS-PAGE.

The protein (1mg/ml) was lyophilized after from a sterile solution containing TBS pH-7.5, 0.1% BSA and 0.09% NaN3. Sterile Filtered White lyophilized (freeze-dried) powder.

Lyophilized RAP Rat although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution RAP Rat should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Special Note: Ligand binding to RAP is Ca2+ dependent and e.g. lipid receptors can be released from RAP by a buffer containing 10mM EDTA. Furthermore, buffers containing phosphate should be avoided (it would form precipitates with Ca2+).

Solubility: It is recommended to reconstitute the lyophilized RAP Rat in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins

Description: Recombinant Rat Receptor Associated Protein produced in E Coli is a single, non-glycosylated polypeptide chain having a molecular mass of 38,862 Dalton. The Recombinant RAP Rat contains 6xHis tag and 1xC-myc, RAP Rat is purified by proprietary chromatographic techniques. Introduction: Receptor-associated Protein (aka RAP) averts the GCM-mediated enhancement of axon growth- ApoE-containing lipoproteins which are known to bind to receptors of the LDLr superfamily. In the presence of RAP, GCM doesn't increase the axon extension rate in relation to base medium. Furthermore, the addition of RAP to the base medium doesn't change the rate of axon extension. This implies that the growth stimulatory effect of apoE-containing lipoproteins secreted by glial cells is mediated by the LDLr family receptors. RAP annuls the growth stimulatory effect of GCM.

30685105

NP_850176.1

NM_179845.3

75,679 Da

Protein contains putative RNA binding domain. Expressed in response to Pseudomonas syringae infection. Resistance requires silencing of AtRAP suggesting it functions as a negative regulator of plant disease resistance.

0.005 mg

140 USD

0.02 mg

205

1 mg

2750