protein

Recombinant Human Fatty Acid Binding Protein-3

MBS142895

0.005 mg

140 USD

Recombinant Protein

Recombinant Human Fatty Acid Binding Protein-3

Fatty Acid Binding Protein-3

FABP3 Human; Fatty Acid Binding Protein-3 Human Recombinant; Fatty acid-binding protein heart; H-FABP; Heart-type fatty acid-binding protein; Muscle fatty acid-binding protein; M-FABP; Mammary-derived growth inhibitor; MDGI; FABP3; FABP11; O-FABP

fatty acid-binding protein, heart; Fatty acid-binding protein, heart; fatty acid-binding protein, heart; Fatty acid-binding protein 3, muscle; fatty acid binding protein 11; heart-type fatty acid-binding protein; mammary-derived growth inhibitor; muscle fatty acid-binding protein; fatty acid binding protein 3, muscle and heart; Fatty acid-binding protein 3; Heart-type fatty acid-binding protein; H-FABP; Mammary-derived growth inhibitor; MDGI; Muscle fatty acid-binding protein; M-FABP

FABP3

FABP3; FABP3; MDGI; FABP11; H-FABP; M-FABP; O-FABP; FABP11; MDGI; H-FABP; MDGI; M-FABP

FABPH_HUMAN

E Coli

133

Greater than 90.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

50mM phosphate borate buffer pH-8. Sterile filtered liquid formulation.

Recombinant FABP3 although stable at 10 degree C for 7 days, should be stored desiccated below -20 degree C for long term periods. Please avoid freeze-thaw cycles.

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; FABP

Description: FABP3 Human Recombinant is a non-glycosylated polypeptide chain produced in E Coli. FABP3 is purified by standard chromatography techniques. Introduction: Recombinant Fatty Acid Binding Protein is a newly introduced plasma marker of acute myocardial infarction (AMI). The plasma kinetics of FABP (15kD) closely resemble those of myoglobin in that elevated plasma concentrations are found within 2 hours after AMI and return to normal generally within 18 to 24 hours. But the concentration of FABP in the skeletal muscle is 20 times lower than in cardiac tissue (for myoglobin the same content for cardiac and skeletal tissue), that makes FABP to be more cardiac specific than myoglobin. This makes FABP a useful biochemical marker for the early assessment or exclusion of AMI. FABP also appears to be a useful plasma marker for the estimation of myocardial infarct size.

4758328

NP_004093.1

NM_004102.3

P05413

14,858 Da

PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450)

The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. [provided by RefSeq, Jul 2008]

FABP3: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Protein type: Lipid-binding. Chromosomal Location of Human Ortholog: 1p33-p32. Cellular Component: extracellular space; cytosol; sarcoplasm. Molecular Function: protein binding; icosatetraenoic acid binding; cytoskeletal protein binding; long-chain fatty acid transporter activity. Biological Process: response to drug; negative regulation of cell proliferation; cholesterol homeostasis; regulation of fatty acid oxidation; fatty acid metabolic process; response to insulin stimulus; phospholipid homeostasis

0.005 mg

140 USD

0.02 mg

205

1 mg

3490