protein

Recombinant Yeast Thioredoxin

MBS142888

0.005 mg

140 USD

Recombinant Protein

Recombinant Yeast Thioredoxin

Thioredoxin

TXN1 Yeast; Thioredoxin Yeast Recombinant; Thioredoxin-1; Thioredoxin I; TR-I; Thioredoxin-2; TRX1; TRX2; YLR043C

thioredoxin TRX1; Thioredoxin-1; thioredoxin TRX1; Thioredoxin I; TR-I; Thioredoxin-2

yTXN1

TRX1; TRX1; LMA1; TRX2; TR-I

TRX1_YEAST

E Coli

103

Greater than 95.0% as determined by SDS-PAGE.

Each mg of protein contains 20mM phosphate buffer pH 7.4. Sterile Lyophilized Powder.

TRX although stable at 4 degree C for 3 weeks, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.

Solubility: It is recommended to reconstitute the lyophilized TRX in sterile 18M Omega -cm H2O. Biological Activity: TRX activity is assayed by measuring the change in absorbance at 650 nm at 25 degree C using 0.13 uM bovine insulin containing 0.33mM DTT (pH 6.5).The specific activity was found to be 5.8units/mg.

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Thioredoxin

Description: Thioredoxin Yeast Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain having a molecular mass of 12.6kDa. Introduction: Thioredoxins are small disulphide-containing redox proteins (within the conserved Cys-Gly-Pro-Cys active site) that have been found in all the kingdoms of living organisms. Thioredoxin contains a single disulfide active site and serves as a general protein disulphide oxidoreductase. Thioredoxins are involved in the first unique step in DNA synthesis. It interacts with a broad range of proteins by a redox mechanism based on reversible oxidation of two cysteine thiol groups to a disulphide, accompanied by the transfer of two electrons and two protons. The net result is the covalent interconversion of a disulphide and a dithiol. It has been suggested that thioredoxin may catalyze the formation of correct disulfides during protein folding because of its ability to act as an efficient oxidoreductant. Trx also provides control over a number of transcription factors affecting cell proliferation and death through a mechanism referred to as redox regulation.

6323072

NP_013144.1

NM_001181930.1

P22217

11,235 Da

Cellular Senescence Pathway (1122657); Cellular Responses To Stress Pathway (1122650); Detoxification Of Reactive Oxygen Species Pathway (1122651); Immune System Pathway (1122519); Inflammasomes Pathway (1122563); Innate Immune System Pathway (1122539); Metabolism Pathway (1122041); Metabolism Of Nucleotides Pathway (1122151); Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor (NLR) Signaling Pathways (1122561); Oxidative Stress Induced Senescence Pathway (1122658)

0.005 mg

140 USD

0.02 mg

205

1 mg

2365